Metal sensing by DNA
Metal ions are essential to many chemical, biological, and environmental processes. In the
past two decades, many DNA-based metal sensors have emerged. While the main …
past two decades, many DNA-based metal sensors have emerged. While the main …
Oxidative stress in bacteria and the central dogma of molecular biology
M Fasnacht, N Polacek - Frontiers in Molecular Biosciences, 2021 - frontiersin.org
Ever since the “great oxidation event,” Earth's cellular life forms had to cope with the danger
of reactive oxygen species (ROS) affecting the integrity of biomolecules and hampering …
of reactive oxygen species (ROS) affecting the integrity of biomolecules and hampering …
RNA structural dynamics as captured by molecular simulations: a comprehensive overview
With both catalytic and genetic functions, ribonucleic acid (RNA) is perhaps the most
pluripotent chemical species in molecular biology, and its functions are intimately linked to …
pluripotent chemical species in molecular biology, and its functions are intimately linked to …
[PDF][PDF] CheckMyMetal: a macromolecular metal-binding validation tool
Metals are essential in many biological processes, and metal ions are modeled in roughly
40% of the macromolecular structures in the Protein Data Bank (PDB). However, a …
40% of the macromolecular structures in the Protein Data Bank (PDB). However, a …
Interchangeable utilization of metals: New perspectives on the impacts of metal ions employed in ancient and extant biomolecules
DGJ Smethurst, N Shcherbik - Journal of Biological Chemistry, 2021 - ASBMB
Metal ions provide considerable functionality across biological systems, and their utilization
within biomolecules has adapted through changes in the chemical environment to maintain …
within biomolecules has adapted through changes in the chemical environment to maintain …
Characterizing metal-binding sites in proteins with X-ray crystallography
Metals have crucial roles in many physiological, pathological, toxicological, pharmaceutical,
and diagnostic processes. Proper handling of metal-containing macromolecule samples for …
and diagnostic processes. Proper handling of metal-containing macromolecule samples for …
Pathway-controlled formation of mesostructured all-DNA colloids and superstructures
DNA has traditionally been used for the programmable design of nanostructures by
exploiting its sequence-defined supramolecular recognition. However, control on larger …
exploiting its sequence-defined supramolecular recognition. However, control on larger …
Polarizable force field for RNA based on the classical drude oscillator
RNA molecules are highly dynamic and capable of adopting a wide range of complex,
folded structures. The factors driving the folding and dynamics of these structures are …
folded structures. The factors driving the folding and dynamics of these structures are …
On the Power and Challenges of Atomistic Molecular Dynamics to Investigate RNA Molecules
RNA molecules play a vital role in biological processes within the cell, with significant
implications for science and medicine. Notably, the biological functions exerted by specific …
implications for science and medicine. Notably, the biological functions exerted by specific …
A potentially abundant junctional RNA motif stabilized by m6A and Mg2+
Abstract N 6-Methyladenosine (m6A) is an abundant post-transcriptional RNA modification
that influences multiple aspects of gene expression. In addition to recruiting proteins, m6A …
that influences multiple aspects of gene expression. In addition to recruiting proteins, m6A …