A guide to plasma membrane solute carrier proteins

MD Pizzagalli, A Bensimon… - The FEBS …, 2021 - Wiley Online Library
This review aims to serve as an introduction to the solute carrier proteins (SLC) superfamily
of transporter proteins and their roles in human cells. The SLC superfamily currently …

Molecular mechanisms of brain water transport

N MacAulay - Nature Reviews Neuroscience, 2021 - nature.com
Our brains consist of 80% water, which is continuously shifted between different
compartments and cell types during physiological and pathophysiological processes …

A relay velocity model infers cell-dependent RNA velocity

S Li, P Zhang, W Chen, L Ye, KW Brannan, NT Le… - Nature …, 2024 - nature.com
RNA velocity provides an approach for inferring cellular state transitions from single-cell
RNA sequencing (scRNA-seq) data. Conventional RNA velocity models infer universal …

The glymphatic system: a beginner's guide

NA Jessen, ASF Munk, I Lundgaard… - Neurochemical …, 2015 - Springer
The glymphatic system is a recently discovered macroscopic waste clearance system that
utilizes a unique system of perivascular tunnels, formed by astroglial cells, to promote …

Cerebrospinal fluid secretion by the choroid plexus

HH Damkier, PD Brown… - Physiological reviews, 2013 - journals.physiology.org
The choroid plexus epithelium is a cuboidal cell monolayer, which produces the majority of
the cerebrospinal fluid. The concerted action of a variety of integral membrane proteins …

Multiplicity of cerebrospinal fluid functions: New challenges in health and disease

CE Johanson, JA Duncan, PM Klinge, T Brinker… - Cerebrospinal fluid …, 2008 - Springer
This review integrates eight aspects of cerebrospinal fluid (CSF) circulatory dynamics:
formation rate, pressure, flow, volume, turnover rate, composition, recycling and …

The SLC4 family of bicarbonate (HCO3-) transporters

MF Romero, AP Chen, MD Parker, WF Boron - Molecular aspects of …, 2013 - Elsevier
The SLC4 family consists of 10 genes (SLC4A1–5; SLC4A7–11). All encode integral
membrane proteins with very similar hydropathy plots—consistent with 10–14 …

The cellular mechanisms of neuronal swelling underlying cytotoxic edema

RL Rungta, HB Choi, JR Tyson, A Malik… - Cell, 2015 - cell.com
Cytotoxic brain edema triggered by neuronal swelling is the chief cause of mortality
following brain trauma and cerebral infarct. Using fluorescence lifetime imaging to analyze …

Molecular biology of the blood-brain and the blood-cerebrospinal fluid barriers: similarities and differences

Z Redzic - Fluids and Barriers of the CNS, 2011 - Springer
Efficient processing of information by the central nervous system (CNS) represents an
important evolutionary advantage. Thus, homeostatic mechanisms have developed that …

Cross-ancestry genome-wide association meta-analyses of hippocampal and subfield volumes

N Liu, L Zhang, T Tian, J Cheng, B Zhang, S Qiu… - Nature …, 2023 - nature.com
The hippocampus is critical for memory and cognition and neuropsychiatric disorders, and
its subfields differ in architecture and function. Genome-wide association studies on …