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Adaptive optics for high-resolution imaging
Adaptive optics (AO) is a technique that corrects for optical aberrations. It was originally
proposed to correct for the blurring effect of atmospheric turbulence on images in ground …
proposed to correct for the blurring effect of atmospheric turbulence on images in ground …
Choriocapillaris: fundamentals and advancements
The choriocapillaris is the innermost structure of the choroid that directly nourishes the
retinal pigment epithelium and photoreceptors. This article provides an overview of its …
retinal pigment epithelium and photoreceptors. This article provides an overview of its …
Twenty-five years of clinical applications using adaptive optics ophthalmoscopy
Twenty-five years ago, adaptive optics (AO) was combined with fundus photography,
thereby initiating a new era in the field of ophthalmic imaging. Since that time, clinical …
thereby initiating a new era in the field of ophthalmic imaging. Since that time, clinical …
Ultrahigh-speed multimodal adaptive optics system for microscopic structural and functional imaging of the human retina
We describe the design and performance of a multimodal and multifunctional adaptive
optics (AO) system that combines scanning laser ophthalmoscopy (SLO) and optical …
optics (AO) system that combines scanning laser ophthalmoscopy (SLO) and optical …
Integrating adaptive optics-SLO and OCT for multimodal visualization of the human retinal pigment epithelial mosaic
In vivo imaging of human retinal pigment epithelial (RPE) cells has been demonstrated
through multiple adaptive optics (AO)-based modalities. However, whether consistent and …
through multiple adaptive optics (AO)-based modalities. However, whether consistent and …
Widespread subclinical cellular changes revealed across a neural-epithelial-vascular complex in choroideremia using adaptive optics
Choroideremia is an X-linked, blinding retinal degeneration with progressive loss of
photoreceptors, retinal pigment epithelial (RPE) cells, and choriocapillaris. To study the …
photoreceptors, retinal pigment epithelial (RPE) cells, and choriocapillaris. To study the …
In-vivo sub-diffraction adaptive optics imaging of photoreceptors in the human eye with annular pupil illumination and sub-Airy detection
Adaptive optics scanning light ophthalmoscopy (AOSLO) allows non-invasive visualization
of the living human eye at the microscopic scale; but even with correction of the ocular …
of the living human eye at the microscopic scale; but even with correction of the ocular …
Current choroidal imaging findings in central serous chorioretinopathy
Background: Central serous chorioretinopathy (CSCR) is a chorioretinal disease affecting
mostly middle age males. It is marked by the serous detachment of the neurosensory layer at …
mostly middle age males. It is marked by the serous detachment of the neurosensory layer at …
Active cell appearance model induced generative adversarial networks for annotation-efficient cell segmentation and identification on adaptive optics retinal images
Data annotation is a fundamental precursor for establishing large training sets to effectively
apply deep learning methods to medical image analysis. For cell segmentation, obtaining …
apply deep learning methods to medical image analysis. For cell segmentation, obtaining …
New developments in angiography for the diagnosis and management of diabetic retinopathy
The most common microvascular complication of diabetes is diabetic retinopathy, the
leading cause of blindness in adults of working age. Our understanding of the vascular …
leading cause of blindness in adults of working age. Our understanding of the vascular …