Cystic fibrosis (CF) represents one of a number of localized lung and non-lung diseases with
an intense chronic inflammatory component associated with evidence of systemic oxidative …

Hypertension (high blood pressure) is a major public health problem affecting more than a
billion people worldwide with complications, including stroke, heart failure and kidney …

Abstract Elexacaftor/tezacaftor/ivacaftor (ETI) is associated with major improvements in
respiratory outcomes of individuals with cystic fibrosis (CF) and at least one Phe508del …

Recent studies suggest that primary changes in vascular resistance can cause sustained
changes in arterial blood pressure. In this review, we summarize current knowledge about …

Cardiovascular diseases can be an emerging complication in cystic fibrosis (CF), as the
median life expectancy has improved considerably. The objective of this study was to …

Cl− and HCO3− are the most prevalent membrane-permeable anions in the intra-and
extracellular spaces of the vascular wall. Outwardly directed electrochemical gradients for …

Background The pathophysiological roles of cystic fibrosis transmembrane-conductance
regulator (CFTR) Cl− channels in the regulation of blood pressure (BP) remain controversial …

Atherosclerosis is a chronic inflammatory disease of the vascular wall. Dysfunction of cystic
fibrosis transmembrane conductance regulator (CFTR) has been shown to result in …

Cystic fibrosis transmembrane conductance regulator (CFTR) is a prominent chloride
channel that governs mucous secretion in multiple organs, including the reproductive tract …

Background: Cystic fibrosis transmembrane conductance regulator (CFTR) has been
associated with vascular tone and blood pressure (BP), however, its role in the genesis of …