From oxidative stress to inflammation in the posterior ocular diseases: diagnosis and treatment

A Dammak, F Huete-Toral, C Carpena-Torres… - Pharmaceutics, 2021 - mdpi.com
Most irreversible blindness observed with glaucoma and retina-related ocular diseases,
including age-related macular degeneration and diabetic retinopathy, have their origin in the …

Role of oxidative stress in sulfur mustard-induced pulmonary injury and antioxidant protection

E Tahmasbpour, S Reza Emami, M Ghanei… - Inhalation …, 2015 - Taylor & Francis
Sulfur mustard (SM) is a potent alkylating agent that targets several organs, especially lung
tissue. Although pathological effects of SM have been widely considered, molecular and …

[HTML][HTML] Identification of early events in nitrogen mustard pulmonary toxicity that are independent of infiltrating inflammatory cells using precision cut lung slices

A Bellomo, J Herbert, MJ Kudlak, JD Laskin… - Toxicology and Applied …, 2024 - Elsevier
Nitrogen mustard (NM; mechlorethamine) is a cytotoxic vesicant known to cause acute lung
injury which can progress to chronic disease. Due to the complex nature of NM injury, it has …

Mustard vesicant-induced lung injury: Advances in therapy

B Weinberger, R Malaviya, VR Sunil, A Venosa… - Toxicology and applied …, 2016 - Elsevier
Most mortality and morbidity following exposure to vesicants such as sulfur mustard is due to
pulmonary toxicity. Acute injury is characterized by epithelial detachment and necrosis in the …

Free radical production and oxidative stress in lung tissue of patients exposed to sulfur mustard: an overview of cellular and molecular mechanisms

A Beigi Harchegani, E Tahmasbpour… - Chemical research in …, 2018 - ACS Publications
Sulfur mustard (SM) is a chemical alkylating compound that primary targets lung tissue. It
causes a wide variety of pathological effects in respiratory system such as chronic bronchitis …

A clinicopathological approach to sulfur mustard-induced organ complications: a major review

H Ghasemi, P Owlia, MR Jalali-Nadoushan… - … and ocular toxicology, 2013 - Taylor & Francis
Abstract Context: Sulfur mustard (SM), with an old manufacturing history still remains as
potential threat due to easy production and extensive effects. Objectives: Increasing studies …

Inhalation of sulfur mustard causes long-term T cell-dependent inflammation: possible role of Th17 cells in chronic lung pathology

NC Mishra, GR Grotendorst, RJ Langley… - International …, 2012 - Elsevier
Sulfur mustard (SM) is a highly toxic chemical warfare agent that remains a threat to human
health. The immediate symptoms of pulmonary distress may develop into chronic lung injury …

Th17/Treg-related cytokine imbalance in sulfur mustard exposed and stable chronic obstructive pulmonary (COPD) patients: correlation with disease activity

S Imani, J Salimian, J Fu, M Ghanei… - Immunopharmacology …, 2016 - Taylor & Francis
In this study, we investigated expression changes of Th17/Treg-related cytokine in
transbronchial lung biopsy (TBLBs) of sulfur mustard (SM) exposure, stable chronic …

Sulfur mustard and biological ageing: A multisystem biological health score approach as an extension of the allostatic load in Sardasht chemical veterans

L Nasiri, MR Vaez-Mahdavi, H Hassanpour… - International …, 2021 - Elsevier
Background Mustard gas as a chemical weapon has been used in wars and its long-term
side effects are substantial in the human body. This study was aimed to apply an extension …

Role of reactive nitrogen species generated via inducible nitric oxide synthase in vesicant-induced lung injury, inflammation and altered lung functioning

VR Sunil, J Shen, K Patel-Vayas, AJ Gow… - Toxicology and applied …, 2012 - Elsevier
Pulmonary toxicity induced by sulfur mustard and related vesicants is associated with
oxidative stress. In the present studies we analyzed the role of reactive nitrogen species …