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Glaucoma: From pathogenic mechanisms to retinal glial cell response to damage
Glaucoma is a neurodegenerative disease of the retina characterized by the irreversible loss
of retinal ganglion cells (RGCs) leading to visual loss. Degeneration of RGCs and loss of …
of retinal ganglion cells (RGCs) leading to visual loss. Degeneration of RGCs and loss of …
Sustained release glaucoma therapies: Novel modalities for overcoming key treatment barriers associated with topical medications
Glaucoma is a progressive optic neuropathy and a leading cause of irreversible blindness.
The disease has conventionally been characterized by an elevated intraocular pressure …
The disease has conventionally been characterized by an elevated intraocular pressure …
Ocular blood flow as a clinical observation: Value, limitations and data analysis
Alterations in ocular blood flow have been identified as important risk factors for the onset
and progression of numerous diseases of the eye. In particular, several population-based …
and progression of numerous diseases of the eye. In particular, several population-based …
[HTML][HTML] Oxidative stress and the role of NADPH oxidase in glaucoma
Glaucoma is characterised by loss of retinal ganglion cells, and their axons and many
pathophysiological processes are postulated to be involved. It is increasingly understood …
pathophysiological processes are postulated to be involved. It is increasingly understood …
Therapeutic ophthalmic lenses: a review
An increasing incidence of eye diseases has been registered in the last decades in
developed countries due to the ageing of population, changes in lifestyle, environmental …
developed countries due to the ageing of population, changes in lifestyle, environmental …
Using genetic mouse models to gain insight into glaucoma: Past results and future possibilities
While all forms of glaucoma are characterized by a specific pattern of retinal ganglion cell
death, they are clinically divided into several distinct subclasses, including normal tension …
death, they are clinically divided into several distinct subclasses, including normal tension …
Blood flow mechanics and oxygen transport and delivery in the retinal microcirculation: multiscale mathematical modeling and numerical simulation
The scientific community continues to accrue evidence that blood flow alterations and
ischemic conditions in the retina play an important role in the pathogenesis of ocular …
ischemic conditions in the retina play an important role in the pathogenesis of ocular …
The role of endogenous neuroprotective mechanisms in the prevention of retinal ganglion cells degeneration
M Pietrucha-Dutczak, M Amadio, S Govoni… - Frontiers in …, 2018 - frontiersin.org
Retinal neurons are not able to undergo spontaneous regeneration in response to damage.
A variety of stressors, ie, UV radiation, high temperature, ischemia, allergens, and others …
A variety of stressors, ie, UV radiation, high temperature, ischemia, allergens, and others …
Systemic diseases and their association with open-angle glaucoma in the population of Stockholm
P Wändell, AC Carlsson, G Ljunggren - International ophthalmology, 2022 - Springer
Objective We aimed to study open-angle glaucoma in association with somatic
comorbidities in the total population of adults in Region Stockholm. Methods The study …
comorbidities in the total population of adults in Region Stockholm. Methods The study …
A time window for rescuing dying retinal ganglion cells
Background Retinal ganglion cell (RGC) degeneration and death cause vision loss in
patients with glaucoma. Regulated cell death, once initiated, is generally considered to be …
patients with glaucoma. Regulated cell death, once initiated, is generally considered to be …