Human epidermal growth factor receptor 2 (HER2) is a member of the epidermal growth
factor receptor family having tyrosine kinase activity. Dimerization of the receptor results in …

The development of cancer is due to the accumulation of multiple somatic mutations and in
some cases due to germline mutations, which occur in malignancies such as retinoblastoma …

Effective antitumour immunity depends on the orchestration of potent T cell responses
against malignancies. Regression of human cancers has been induced by immune …

Blocking the HER2 signaling pathway has been an effective strategy in the treatment of
HER2‐positive breast cancer. It mainly relies on the use of monoclonal antibodies and …

Human epidermal growth factor receptor-2 (HER2/erbB-2) belongs to a family of four
transmembrane receptors involved in signal transduction pathways that regulate cell growth …

The epithelial ovarian carcinomas, which make up more than 85% of human ovarian cancer,
arise in the ovarian surface epithelium (OSE). The etiology and early events in the …

Ovarian cancer varies widely in frequency among different geographic regions and ethnic
groups, with a high incidence in Northern Europe and the United States, and a low …

The gene known as neu, erbB-2, or HER-2 is among those most frequently altered in human
cancer, neu was first identified as a transforming gene activated in chemically induced rat …

Homeostasis of multicellular organisms is critically dependent on the correct interpretation of
the plethora of signals which cells are exposed to during their lifespan. Various soluble …

Branched gold nanoparticles are potential photothermal therapy agents because of their
large absorption cross section in the near-infrared window. Upon laser irradiation they …