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Skeletal and extraskeletal actions of vitamin D: current evidence and outstanding questions
The etiology of endemic rickets was discovered a century ago. Vitamin D is the precursor of
25-hydroxyvitamin D and other metabolites, including 1, 25 (OH) 2D, the ligand for the …
25-hydroxyvitamin D and other metabolites, including 1, 25 (OH) 2D, the ligand for the …
[HTML][HTML] Vitamin D supplementation and total cancer incidence and mortality: a meta-analysis of randomized controlled trials
Background Previous meta-analyses of randomized controlled trials (RCTs) of vitamin D
supplementation and total cancer incidence and mortality found inconsistent results, and …
supplementation and total cancer incidence and mortality found inconsistent results, and …
Vitamin D regulates microbiome-dependent cancer immunity
A role for vitamin D in immune modulation and in cancer has been suggested. In this work,
we report that mice with increased availability of vitamin D display greater immune …
we report that mice with increased availability of vitamin D display greater immune …
Vitamin D supplementation and cardiovascular disease risks in more than 83 000 individuals in 21 randomized clinical trials: a meta-analysis
Importance Observational studies have reported an association between low serum vitamin
D levels and elevated risk of cardiovascular disease (CVD) events, but such studies cannot …
D levels and elevated risk of cardiovascular disease (CVD) events, but such studies cannot …
Hormones and aging: an endocrine society scientific statement
Multiple changes occur across various endocrine systems as an individual ages. The
understanding of the factors that cause age-related changes and how they should be …
understanding of the factors that cause age-related changes and how they should be …
[HTML][HTML] Vitamin D: an overview of gene regulation, ranging from metabolism to genomic effects
Vitamin D is a pro-hormone characterized by an intricate metabolism and regulation. It is
well known for its role in calcium and phosphate metabolism, and in bone health. However …
well known for its role in calcium and phosphate metabolism, and in bone health. However …
Effect of monthly high-dose vitamin D supplementation on cardiovascular disease in the vitamin D assessment study: a randomized clinical trial
Importance Cohort studies have reported increased incidence of cardiovascular disease
(CVD) among individuals with low vitamin D status. To date, randomized clinical trials of …
(CVD) among individuals with low vitamin D status. To date, randomized clinical trials of …
Controversies in vitamin D: summary statement from an international conference
Context Vitamin D is classically recognized as a regulator of calcium and phosphorus
metabolism. Recent advances in the measurement of vitamin D metabolites, diagnosis of …
metabolism. Recent advances in the measurement of vitamin D metabolites, diagnosis of …
Vitamin D and risk of cause specific death: systematic review and meta-analysis of observational cohort and randomised intervention studies
Objective To evaluate the extent to which circulating biomarker and supplements of vitamin
D are associated with mortality from cardiovascular, cancer, or other conditions, under …
D are associated with mortality from cardiovascular, cancer, or other conditions, under …
Vitamin D and multiple health outcomes: umbrella review of systematic reviews and meta-analyses of observational studies and randomised trials
Objective To evaluate the breadth, validity, and presence of biases of the associations of
vitamin D with diverse outcomes. Design Umbrella review of the evidence across systematic …
vitamin D with diverse outcomes. Design Umbrella review of the evidence across systematic …