Considerable evidence supports the role of oxidative stress in adult type 2 diabetes (T2D).
Due to increasing rates of pediatric obesity, lack of physical activity, and consumption of …

The discovery of proper molecular signature from OMIC data is indispensable for
determining biological state, physiological condition, disease etiology, and therapeutic …

The pathophysiology of diabetic macular oedema (DME) remains poorly understood.
Proteomic analysis of the vitreous using mass spectrometry (MS) can potentially identify …

Analysis of differential abundance in proteomics data sets requires careful application of
missing value imputation. Missing abundance values widely vary when performing …

Spatially targeted proteomics analyzes the proteome of specific cell types and functional
regions within tissue. While spatial context is often essential to understanding biological …

As one of the widespread RNA post-transcriptional modifications (PTCMs), 5-Methylcytosine
(m5C) plays vital roles in better understanding of basic biological mechanisms and major …

Background Shenzhu Tiaopi granule (STG) has antidiabetic functions. Data-independent
acquisition proteomic technology is an integral part of systems biology. Herein, proteomics …

The applicability and benefits of pancreatic islet transplantation are limited due to various
issues including the need to avoid immune-mediated rejection. Here, we used our …

Pulmonary arterial hypertension (PAH) is a severe and progressive disease that affects the
heart and lungs and a global health concern that impacts individuals and society. Studies …

BACKGROUND Only 50% of patients with type 2 diabetes mellitus (T2DM) can control their
blood glucose levels. Dapagliflozin is a selective inhibitor of sodium-glucose co-transporter …