The present review article offers a detailed account of the design strategies employed for the
synthesis of nitrogen-containing anticancer agents. The results of different studies describe …

Benzimidazole, a fused heterocycle bearing benzene and imidazole has gained
considerable attention in the field of contemporary medicinal chemistry. The moiety is of …

Cancer is one of the leading causes of death worldwide. Mutation of the cell regulates genes
and protein causing cancer. Surgery, radiotherapy, and the use of anticancer agents are the …

Microtubules are protein biopolymers formed through polymerization of heterodimers of α-
and β-tubulins. Disruption of microtubules can induce cell cycle arrest in G 2-M phase and …

Cancer is one of the most serious medical problem and second leading cause of death in
the world, characterized by a deregulation of the cell cycle which mainly results in a …

In the present study, three novel fluorinated terphenyl compounds ie, 2′, 4, 4′′, 5′-
tetrafluoro-1, 1': 4′, 1′′-terphenyl (1), 2′, 5′-difluoro-1, 1': 4′, 1′′-terphenyl (2) and …

A series of new β-carboline-dithiocarbamate derivatives bearing phenyl, dithiocarbamate
and H/methyl substitutions at position-1, 3 and 9, respectively, were designed and …

Bioorthogonal cleavage reactions have been developed as an intriguing strategy to
enhance the safety of chemotherapeutics. Aiming to reduce the toxicity and improve the …

The synthesis of some new morpholine-benzimidazole-pyrazole hybrids (8a-o) and their in
vitro anticancer activity against three human cancer cell lines like breast (MCF7), prostate …

(Benz) imidazoles can be efficiently functionalized by (hetero) aryl chlorides via direct C–H
bond arylation in the presence of a well-defined NHC-Pd (II)-Im complex. Under the optimal …