Human schistosomes combat the unique immune systems of two vastly different hosts
during their indirect life cycles. In gastropod molluscs, they face a potent innate immune …

This review reexamines the results obtained in recent decades regarding the compatibility
polymorphism between the snail, Biomphalaria glabrata, and the pathogen, Schistosoma …

Biomphalaria snails are instrumental in transmission of the human blood fluke Schistosoma
mansoni. With the World Health Organization's goal to eliminate schistosomiasis as a global …

Timothy Doran's 11-year-old daughter is allergic to eggs. And like about 2% of children
worldwide who share the condition, she is unable to receive many routine vaccinations …

Background Biomphalaria pfeifferi is the world's most widely distributed and commonly
implicated vector snail species for the causative agent of human intestinal schistosomiasis …

Schistosomiasis, a devastating disease caused by parasitic flatworms of the genus
Schistosoma, affects over 260 million people worldwide especially in tropical and sub …

The freshwater snail Biomphalaria glabrata is an important intermediate host of the parasite
Schistosoma mansoni that causes human intestinal schistosomiasis. To better understand …

The snail's immune response is an important determinant of schistosome infection success,
acting in concert with host, parasite, and environmental factors. Coordinated by haemocytes …

The trematodes that cause schistosomiasis in humans require aquatic snails as intermediate
hosts. Identifying the genes in snails at which allelic variation controls resistance to infection …

Comparative immunology, studying both vertebrates and invertebrates, provided the earliest
descriptions of phagocytosis as a general immune mechanism. However, the large scale of …