Biological utility of fluorinated compounds: from materials design to molecular imaging, therapeutics and environmental remediation

C Zhang, K Yan, C Fu, H Peng, CJ Hawker… - Chemical …, 2021 - ACS Publications
The applications of fluorinated molecules in bioengineering and nanotechnology are
expanding rapidly with the controlled introduction of fluorine being broadly studied due to …

Inorganic nanomaterials with rapid clearance for biomedical applications

X Wang, X Zhong, J Li, Z Liu, L Cheng - Chemical Society Reviews, 2021 - pubs.rsc.org
Inorganic nanomaterials that have inherently exceptional physicochemical properties (eg,
catalytic, optical, thermal, electrical, or magnetic performance) that can provide desirable …

Coordination-driven self-assembly strategy-activated Cu single-atom nanozymes for catalytic tumor-specific therapy

J Zhou, D Xu, G Tian, Q He, X Zhang… - Journal of the …, 2023 - ACS Publications
How to optimize the enzyme-like catalytic activity of nanozymes to improve their applicability
has become a great challenge. Herein, we present an l-cysteine (l-Cys) coordination-driven …

Synthetic amorphous silica nanoparticles: toxicity, biomedical and environmental implications

JG Croissant, KS Butler, JI Zink, CJ Brinker - Nature Reviews Materials, 2020 - nature.com
Natural silica and silicates are predominantly crystalline and constitute the most abundant
components of the Earth's crust. Man-made silica is typically amorphous and manufactured …

Reactive oxygen species (ROS)-based nanomedicine

B Yang, Y Chen, J Shi - Chemical reviews, 2019 - ACS Publications
Reactive oxygen species (ROS) play an essential role in regulating various physiological
functions of living organisms. The intrinsic biochemical properties of ROS, which underlie …

Development of nanotechnology-mediated precision radiotherapy for anti-metastasis and radioprotection

Y Pan, W Tang, W Fan, J Zhang, X Chen - Chemical Society Reviews, 2022 - pubs.rsc.org
Radiotherapy (RT), including external beam RT and internal radiation therapy, uses high-
energy ionizing radiation to kill tumor cells. However, ionizing radiation inevitably damages …

Magnetic targeting, tumor microenvironment-responsive intelligent nanocatalysts for enhanced tumor ablation

L Feng, R **e, C Wang, S Gai, F He, D Yang, P Yang… - ACS …, 2018 - ACS Publications
Therapeutic nanosystems which can be triggered by the distinctive tumor microenvironment
possess great selectivity and safety to treat cancers via in situ transformation of nontoxic …

Degradability and clearance of inorganic nanoparticles for biomedical applications

G Yang, SZF Phua, AK Bindra, Y Zhao - Advanced Materials, 2019 - Wiley Online Library
Inorganic nanoparticles with tunable and diverse properties hold tremendous potential in the
field of nanomedicine, while having non‐negligible toxicity concerns in healthy …

The coppery age: copper (Cu)‐involved nanotheranostics

C Dong, W Feng, W Xu, L Yu, H **ang… - Advanced …, 2020 - Wiley Online Library
As an essential trace element in the human body, transitional metal copper (Cu) ions are the
bioactive components within the body featuring dedicated biological effects such as …

Recent advances in near-infrared-II hollow nanoplatforms for photothermal-based cancer treatment

L Zhang, G Oudeng, F Wen, G Liao - Biomaterials Research, 2022 - spj.science.org
Abstract Near-infrared-II (NIR-II, 1000–1700 nm) light-triggered photothermal therapy (PTT)
has been regarded as a promising candidate for cancer treatment, but PTT alone often fails …