Photobiomodulation in experimental models of Alzheimer's disease: state-of-the-art and translational perspectives

Z Huang, MR Hamblin, Q Zhang - Alzheimer's Research & Therapy, 2024 - Springer
Alzheimer's disease (AD) poses a significant public health problem, affecting millions of
people across the world. Despite decades of research into therapeutic strategies for AD …

The benefits of exercise for outcome improvement following traumatic brain injury: evidence, pitfalls and future perspectives

Y Zhang, Z Huang, H **a, J **ong, X Ma, C Liu - Experimental Neurology, 2022 - Elsevier
Traumatic brain injury (TBI), also known as a silent epidemic, is currently a substantial public
health problem worldwide. Given the increased energy demands following brain injury …

Non-invasive photobiomodulation treatment in an Alzheimer Disease-like transgenic rat model

L Yang, C Wu, E Parker, Y Li, Y Dong, L Tucker… - …, 2022 - pmc.ncbi.nlm.nih.gov
Alzheimer's disease (AD) is the most common form of dementia in the elderly, causing
neuronal degeneration and cognitive deficits that significantly impair independence and …

Photobiomodulation treatment inhibits neurotoxic astrocytic polarization and protects neurons in in vitro and in vivo stroke models

Y Feng, L Yang, X Ma, Z Huang, X Zong… - Neurochemistry …, 2023 - Elsevier
The beneficial effects of photobiomodulation (PBM) on function recovery after stroke have
been well-established, while its molecular and cellular mechanisms remain to be elucidated …

Methylene blue pretreatment protects against repeated neonatal isoflurane exposure-induced brain injury and memory loss

C Wu, Q Deng, L Zhu, TC Liu, R Duan, L Yang - Molecular Neurobiology, 2024 - Springer
Perioperative neurocognitive impairment (PND) is a common medical complication in the
postoperative period. General anesthesia through volatile anesthetics poses a high risk of …

Photobiomodulation attenuates oligodendrocyte dysfunction and prevents adverse neurological consequences in a rat model of early life adversity

Z Huang, Y Zhang, X Ma, Y Feng, X Zong… - …, 2023 - pmc.ncbi.nlm.nih.gov
Rationale: Adverse experiences in early life including abuse, trauma and neglect, have
been linked to poor physical and mental health outcomes. Emerging evidence implies that …

Photobiomodulation augments the effects of mitochondrial transplantation in the treatment of spinal cord injury in rats by facilitating mitochondrial transfer to neurons …

Z Zhu, X Li, X Wang, X Zuo, Y Ma, X Gao… - Bioengineering & …, 2023 - Wiley Online Library
Mitochondrial transplantation is a promising treatment for spinal cord injury (SCI), but it has
the disadvantage of low efficiency of mitochondrial transfer to targeted cells. Here, we …

Activation of testosterone‐androgen receptor mediates cerebrovascular protection by photobiomodulation treatment in photothrombosis‐induced stroke rats

Y Feng, Z Huang, X Ma, X Zong… - CNS Neuroscience …, 2024 - Wiley Online Library
Rationale Numerous epidemiological studies have reported a link between low testosterone
levels and an increased risk of cerebrovascular disease in men. However, there is ongoing …

Preventing Post-Traumatic Stress Disorder (PTSD) in rats with pulsed 810 nm laser transcranial phototherapy

H Zhao, Y Li, T Luo, W Chou, T Sun, H Liu… - Translational …, 2023 - nature.com
Post-traumatic stress disorder (PTSD) is a debilitating condition that occurs following
exposure to traumatic events. Current treatments, such as psychological debriefing and …

Therapeutic non-invasive brain treatments in Alzheimer's disease: Recent advances and challenges

C Wu, L Yang, S Feng, L Zhu, L Yang, TCY Liu… - Inflammation and …, 2022 - Springer
Alzheimer's disease (AD) is one of the major neurodegenerative diseases and the most
common form of dementia. Characterized by the loss of learning, memory, problem-solving …