Virological and immunological outcomes of coinfections
Coinfections involving viruses are being recognized to influence the disease pattern that
occurs relative to that with single infection. Classically, we usually think of a clinical …
occurs relative to that with single infection. Classically, we usually think of a clinical …
Applications of flow cytometry to clinical microbiology
Classical microbiology techniques are relatively slow in comparison to other analytical
techniques, in many cases due to the need to culture the microorganisms. Furthermore …
techniques, in many cases due to the need to culture the microorganisms. Furthermore …
HIV-1 Nef protein protects infected primary cells against killing by cytotoxic T lymphocytes
Cytotoxic T lymphocytes (CTLs) lyse virally infected cells that display viral peptide epitopes
in association with major histocompatibility complex (MHC) class I molecules on the cell …
in association with major histocompatibility complex (MHC) class I molecules on the cell …
The selective downregulation of class I major histocompatibility complex proteins by HIV-1 protects HIV-infected cells from NK cells
GB Cohen, RT Gandhi, DM Davis, O Mandelboim… - Immunity, 1999 - cell.com
To avoid detection by CTL, HIV encodes mechanisms for removal of class I MHC proteins
from the surface of infected cells. However, class I downregulation potentially exposes the …
from the surface of infected cells. However, class I downregulation potentially exposes the …
Cell-to-cell spread of HIV permits ongoing replication despite antiretroviral therapy
Latency and ongoing replication have both been proposed to explain the drug-insensitive
human immunodeficiency virus (HIV) reservoir maintained during antiretroviral therapy …
human immunodeficiency virus (HIV) reservoir maintained during antiretroviral therapy …
A novel human WD protein, h-βTrCP, that interacts with HIV-1 Vpu connects CD4 to the ER degradation pathway through an F-box motif
HIV-1 Vpu interacts with CD4 in the endoplasmic reticulum and triggers CD4 degradation,
presumably by proteasomes. Human βTrCP identified by interaction with Vpu connects CD4 …
presumably by proteasomes. Human βTrCP identified by interaction with Vpu connects CD4 …
[BOOK][B] HIV and the pathogenesis of AIDS.
JA Levy - 1994 - cabidigitallibrary.org
This book grew out of a scientific review, originally published in Microbiological Reviews. It
has been updated and expanded-now citing more than 2100 references (100 pages of the …
has been updated and expanded-now citing more than 2100 references (100 pages of the …
HIV-infected T cells are migratory vehicles for viral dissemination
After host entry through mucosal surfaces, human immunodeficiency virus-1 (HIV-1)
disseminates to lymphoid tissues to establish a generalized infection of the immune system …
disseminates to lymphoid tissues to establish a generalized infection of the immune system …
Charting HIV's remarkable voyage through the cell: Basic science as a passport to future therapy
WC Greene, BM Peterlin - Nature medicine, 2002 - nature.com
Adequate control of HIV requires impairing the infection, replication and spread of the virus,
no small task given the extraordinary capacity of HIV to exploit the cell's molecular …
no small task given the extraordinary capacity of HIV to exploit the cell's molecular …
Cell-surface expression of CD4 reduces HIV-1 infectivity by blocking Env incorporation in a Nef-and Vpu-inhibitable manner
Abstract Background: Human immunodeficiency virus-1 (HIV-1) infection decreases the cell-
surface expression of its cellular receptor, CD4, through the combined actions of Nef, Env …
surface expression of its cellular receptor, CD4, through the combined actions of Nef, Env …