This manuscript represents a review of lymphoblastic leukemia/lymphoma (acute
lymphoblastic leukemia/lymphoblastic lymphoma), acute leukemias of ambiguous lineage …

Primary vitreoretinal lymphoma (PVRL), also known as primary intraocular lymphoma, is a
rare malignancy typically classified as a diffuse large B‐cell lymphoma and most frequently …

Proteins in the B cell CLL/lymphoma 2 (BCL-2) family are key regulators of the apoptotic
process. This family comprises proapoptotic and prosurvival proteins, and shifting the …

Purpose Approximately 5% of diffuse large B-cell lymphomas (DLBCLs) are double-hit
lymphomas (DHLs) with translocations of both MYC and BCL2. DHLs are characterized by …

Follicular lymphoma (FL) and the GCB subtype of diffuse large B-cell lymphoma (DLBCL)
derive from germinal center B cells. Targeted resequencing studies have revealed mutations …

Background The addition of rituximab to combination chemotherapy with
cyclophosphamide, doxorubicin, vincristine, and prednisone (CHOP), or R-CHOP, has …

Research over the past decade has suggested important roles for pseudogenes in
physiology and disease. In vitro experiments demonstrated that pseudogenes contribute to …

Mutations disabling the TP53 tumour suppressor gene represent the most frequent events in
human cancer and typically occur through a two-hit mechanism involving a missense …

Gene-expression profiling has been used to define 3 molecular subtypes of diffuse large B-
cell lymphoma (DLBCL), termed germinal center B-cell-like (GCB) DLBCL, activated B-cell …

Background The distinction between Burkitt's lymphoma and diffuse large-B-cell lymphoma
is unclear. We used transcriptional and genomic profiling to define Burkitt's lymphoma more …