Alzheimer's disease, the leading cause of dementia in the elderly, is a neurodegenerative
condition characterized by accumulation of amyloid plaques and neurofibrillary tangles in …

The blood coagulation protein fibrinogen is deposited in the brain in a wide range of
neurological diseases and traumatic injuries with blood–brain barrier (BBB) disruption …

In Alzheimer's disease (AD), Aβ deposits form slowly, several decades before further
pathological events trigger neurodegeneration and dementia. However, a substantial …

Alzheimer's disease (AD) is the most common form of dementia and has no effective
treatment. Besides the well-known pathologic characteristics, this disease also has a …

Alzheimer's disease (AD) is the most common form of age-related dementias. In addition to
genetics, environment, and lifestyle, growing evidence supports vascular contributions to …

Since the successful conquest of many acute, communicable (infectious) diseases through
the use of vaccines and antibiotics, the currently most prevalent diseases are chronic and …

The intactness of blood–brain barrier (BBB) is compromised in Alzheimer's disease (AD).
Importantly, evidence suggests that the perturbation and abnormalities appearing in BBB …

The fundamental pathology in Alzheimer's disease (AD) is neuronal dysfunction leading to
cognitive impairment. The amyloid-β peptide (Aβ), derived from amyloid precursor protein, is …

Alzheimer's disease (AD) is the most common neurodegenerative disease, affecting millions
of people worldwide. The classical hallmarks of AD include extracellular beta-amyloid (Aβ) …

Preeclampsia (PE) is a complex, multisystem disorder that remains a leading cause of
morbidity and mortality in pregnancy. Four main classes of dysregulation accompany PE …