Latest advances in cryogel technology for biomedical applications

A Memic, T Colombani, LJ Eggermont… - Advanced …, 2019 - Wiley Online Library
There exists a technological need for advanced materials with improved properties for
emerging biomedical applications. Recent developments in macroporous materials have …

A comprehensive review of cryogels and their roles in tissue engineering applications

KR Hixon, T Lu, SA Sell - Acta biomaterialia, 2017 - Elsevier
The extracellular matrix is fundamental in providing an appropriate environment for cell
interaction and signaling to occur. Replicating such a matrix is advantageous in the support …

Injectable cryogels for biomedical applications

LJ Eggermont, ZJ Rogers, T Colombani, A Memic… - Trends in …, 2020 - cell.com
To prevent postoperative complications, there has been a substantial interest in designing
syringe-injectable hydrogels. To date, cryogels remain the only viable option for preformed …

[HTML][HTML] Design and assessment of biodegradable macroporous cryogels as advanced tissue engineering and drug carrying materials

IN Savina, M Zoughaib, AA Yergeshov - Gels, 2021 - mdpi.com
Cryogels obtained by the cryotropic gelation process are macroporous hydrogels with a well-
developed system of interconnected pores and shape memory. There have been significant …

[HTML][HTML] An overview on collagen and gelatin-based cryogels: Fabrication, classification, properties and biomedical applications

Y He, C Wang, C Wang, Y **ao, W Lin - Polymers, 2021 - mdpi.com
Decades of research into cryogels have resulted in the development of many types of
cryogels for various applications. Collagen and gelatin possess nontoxicity, intrinsic gel …

[HTML][HTML] Cryogel scaffolds for tissue-engineering: Advances and challenges for effective bone and cartilage regeneration

VC Carriero, L Di Muzio, S Petralito, MA Casadei… - Gels, 2023 - mdpi.com
Critical-sized bone defects and articular cartilage injuries resulting from trauma,
osteonecrosis, or age-related degeneration can be often non-healed by physiological …

Injectable cryogels in biomedicine

D Çimen, MA Özbek, N Bereli, B Mattiasson, A Denizli - Gels, 2021 - mdpi.com
Cryogels are interconnected macroporous materials that are synthesized from a monomer
solution at sub-zero temperatures. Cryogels, which are used in various applications in many …

Cryogel scaffolds from patient-specific 3D-printed molds for personalized tissue-engineered bone regeneration in pediatric cleft-craniofacial defects

KR Hixon, AM Melvin, AY Lin… - Journal of …, 2017 - journals.sagepub.com
Bone defects are extremely common in children with cleft-craniofacial conditions, especially
those with alveolar cleft defects and cranial defects. This study used patient-specific 3D …

[HTML][HTML] Investigating manuka honey antibacterial properties when incorporated into cryogel, hydrogel, and electrospun tissue engineering scaffolds

KR Hixon, SJ Bogner, G Ronning-Arnesen… - Gels, 2019 - mdpi.com
Honey is well-known for its wound healing capability and Manuka honey (MH) contains a
unique Manuka factor, providing an additional antibacterial agent. Previously, there has not …

A comparison of tissue engineering scaffolds incorporated with Manuka honey of varying UMF

KR Hixon, T Lu, SH McBride-Gagyi… - BioMed research …, 2017 - Wiley Online Library
Purpose. Manuka honey (MH) is an antibacterial agent specific to the islands of New
Zealand containing both hydrogen peroxide and a Unique Manuka Factor (UMF). Although …