A comprehensive review on the applications of nano-biosensor-based approaches for non-communicable and communicable disease detection
The outstretched applications of biosensors in diverse domains has become the reason for
their attraction for scientific communities. Because they are analytical devices, they can …
their attraction for scientific communities. Because they are analytical devices, they can …
Alkaloids as potential antivirals. A comprehensive review
Alkaloids are a diverse group of natural phytochemicals. These phytochemicals in plants
provide them protection against pests, and herbivorous organisms and also control their …
provide them protection against pests, and herbivorous organisms and also control their …
Neuroligin-3: a circuit-specific synapse organizer that shapes normal function and autism spectrum disorder-associated dysfunction
M Uchigashima, A Cheung, K Futai - Frontiers in Molecular …, 2021 - frontiersin.org
Chemical synapses provide a vital foundation for neuron-neuron communication and overall
brain function. By tethering closely apposed molecular machinery for presynaptic …
brain function. By tethering closely apposed molecular machinery for presynaptic …
Advances in Nonviral mRNA Delivery Materials and Their Application as Vaccines for Melanoma Therapy
Messenger RNA (mRNA) vaccines are promising platforms for cancer immunotherapy
because of their potential to encode for a variety of tumor antigens, high tolerability, and …
because of their potential to encode for a variety of tumor antigens, high tolerability, and …
Control of the eIF4E activity: structural insights and pharmacological implications
The central role of eukaryotic translation initiation factor 4E (eIF4E) in controlling mRNA
translation has been clearly assessed in the last decades. eIF4E function is essential for …
translation has been clearly assessed in the last decades. eIF4E function is essential for …
Update on the development of MNK inhibitors as therapeutic agents
Mitogen-activated protein kinase-interacting kinases 1 and 2 (MNK1/2) represent a central
class of enzymes that are activated by extracellular signal-regulated kinase (ERK) or p38 …
class of enzymes that are activated by extracellular signal-regulated kinase (ERK) or p38 …
Sleep and memory: The impact of sleep deprivation on transcription, translational control, and protein synthesis in the brain
In countries around the world, sleep deprivation represents a widespread problem affecting
school‐age children, teenagers, and adults. Acute sleep deprivation and more chronic sleep …
school‐age children, teenagers, and adults. Acute sleep deprivation and more chronic sleep …
Pharmacological manipulation of translation as a therapeutic target for chronic pain
Dysfunction in regulation of mRNA translation is an increasingly recognized characteristic of
many diseases and disorders, including cancer, diabetes, autoimmunity …
many diseases and disorders, including cancer, diabetes, autoimmunity …
The diversity, plasticity, and adaptability of cap-dependent translation initiation and the associated machinery
KLB Borden, L Volpon - RNA biology, 2020 - Taylor & Francis
Translation initiation is a critical facet of gene expression with important impacts that
underlie cellular responses to stresses and environmental cues. Its dysregulation in many …
underlie cellular responses to stresses and environmental cues. Its dysregulation in many …
Translation dysregulation in neurodegenerative diseases: a focus on ALS
RNA translation is tightly controlled in eukaryotic cells to regulate gene expression and
maintain proteome homeostasis. RNA binding proteins, translation factors, and cell …
maintain proteome homeostasis. RNA binding proteins, translation factors, and cell …