The Anaphase Promoting Complex (APC), a multi-subunit ubiquitin ligase, facilitates mitotic
and G1 progression, and is now recognized to play a role in maintaining genomic stability …

F-box proteins are involved in multiple cellular processes through ubiquitylation and
consequent degradation of targeted substrates. Any significant mutation in F-box protein …

Mycoplasma ovipneumoniae contributes to polymicrobial pneumonia in domestic sheep.
Elucidation of host genetic influences of M. ovipneumoniae nasal detection has the potential …

Probiotics represents a promising intestinal microbiota-targeted therapeutic method for the
treatment of ulcerative colitis (UC). Several lines of evidence implicate that Bifidobacterium …

Adoption of plant-derived compounds for the management of oral cancer is encouraged by
the scientific community due to emerging chemoresistance and conventional treatments …

The anaphase‐promoting complex/cyclosome (APC/C) is an E3 ubiquitin ligase that helps
control chromosome separation and exit from mitosis in many different kinds of organisms …

Compared to other types of lung cancer, lung adenocarcinoma patients with a history of
smoking have a poor prognosis during the treatment of lung cancer. How lung …

E2 ubiquitin conjugating enzymes and E3 ubiquitin ligases play important roles in the
growth and development of plants and animals. To date, the systematic analysis of E2 and …

Iron in excess can have toxic effects on living organisms. In China, the freshwater crayfish
Procambarus clarkii is a source of aquatic food with high-quality protein and has significant …

In the present chapter we discuss the essential roles of the human E3 ubiquitin ligase
Anaphase Promoting Complex/Cyclosome (APC/C) in mitosis as well as the emerging …