Machine learning for antimicrobial peptide identification and design

F Wan, F Wong, JJ Collins… - Nature Reviews …, 2024 - nature.com
Artificial intelligence (AI) and machine learning (ML) models are being deployed in many
domains of society and have recently reached the field of drug discovery. Given the …

Recent advances to combat ESKAPE pathogens with special reference to essential oils

SK Panda, S Buroni, SS Swain, A Bonacorsi… - Frontiers in …, 2022 - frontiersin.org
Biofilm-associated bacteria, especially ESKAPE pathogens (Enterococcus faecium,
Staphylococcus aureus, Klebsiella pneumoniae, Acinetobacter baumannii, Pseudomonas …

LL-37: structures, antimicrobial activity, and influence on amyloid-related diseases

S Bhattacharjya, Z Zhang, A Ramamoorthy - Biomolecules, 2024 - mdpi.com
Antimicrobial peptides (AMPs), as well as host defense peptides (HDPs), constitute the first
line of defense as part of the innate immune system. Humans are known to express …

Artificial intelligence-driven antimicrobial peptide discovery

P Szymczak, E Szczurek - Current Opinion in Structural Biology, 2023 - Elsevier
Antimicrobial peptides (AMPs) emerge as promising agents against antimicrobial resistance,
providing an alternative to conventional antibiotics. Artificial intelligence (AI) revolutionized …

Design and synthesis of bioinspired nanomaterials for biomedical application

K Tang, J Xue, Y Zhu, C Wu - Wiley Interdisciplinary Reviews …, 2024 - Wiley Online Library
Natural materials and bioprocesses provide abundant inspirations for the design and
synthesis of high‐performance nanomaterials. In the past several decades, bioinspired …

Recent development and fighting strategies for lincosamide antibiotic resistance

Y Yang, S **e, F He, Y Xu, Z Wang… - Clinical Microbiology …, 2024 - journals.asm.org
Lincosamides constitute an important class of antibiotics used against a wide range of
pathogens, including methicillin-resistant Staphylococcus aureus. However, due to the …

Prediction and bioactivity of small-molecule antimicrobial peptides from Protaetia brevitarsis Lewis larvae

Q Fu, D Cao, J Sun, X Liu, H Li, C Shu… - Frontiers in Microbiology, 2023 - frontiersin.org
Antimicrobial peptides (AMPs) are widely recognized as promising natural antimicrobial
agents. Insects, as the group of animals with the largest population, have great potential as a …

[HTML][HTML] Molecular interactions, elastic properties, and nanostructure of Langmuir bacterial-lipid monolayers: Towards solving the mystery in bacterial membrane …

X Guo, WH Briscoe - Current Opinion in Colloid & Interface Science, 2023 - Elsevier
The membrane of Gram-negative bacteria (GNB) is especially robust due to the additional,
unique, highly asymmetric outer membrane, with lipopolysaccharides (LPSs) as the main …

Artificial intelligence using a latent diffusion model enables the generation of diverse and potent antimicrobial peptides

Y Wang, M Song, F Liu, Z Liang, R Hong, Y Dong… - Science …, 2025 - science.org
Artificial intelligence holds great promise for the design of antimicrobial peptides (AMPs);
however, current models face limitations in generating AMPs with sufficient novelty and …

[HTML][HTML] Characterization and classification in silico of peptides with dual activity (antimicrobial and wound healing)

M Trejos, Y Aristizabal, A Aragón-Muriel… - International Journal of …, 2023 - mdpi.com
The growing challenge of chronic wounds and antibiotic resistance has spotlighted the
potential of dual-function peptides (antimicrobial and wound healing) as novel therapeutic …