Heat shock protein (HSP) 90 is the most abundant HSPs, which are chaperone molecules
whose major roles are cell protection and maintenance by means of aiding the folding, the …

Cucurbitacins are a class of secondary metabolites initially isolated from the Cucurbitaceae
family. They are important for their analgesic, anti-inflammatory, antimicrobial, antiviral, and …

Polyphenols based bioactive compounds from vegetables and fruits are known for
impressive antioxidant activity. Ingestion of these antioxidants may promote human health …

Many energy metabolism pathways exist in cancer, including glycolysis, amino acid
metabolism, fatty acid oxidation, and mitochondrial respiration. Tumor cells mainly generate …

MicroRNAs (miRNAs) are small, non-coding RNAs about 22 nucleotides in length that
regulate the expression of target genes post-transcriptionally, and are highly involved in …

Research over decades has enabled us in develo** a better understanding of the
multifaceted and heterogeneous nature of cancer. High-throughput technologies have …

Cucurbitacins, widely found in plants belonging to the family of Cucurbitaceae, are highly
oxidized tetracyclic triterpenes with various bioactivities, such as anticancer, anti …

There is increasing evidence suggesting the role of microbiome alterations in relation to
pancreatic adenocarcinoma and tumor immune functionality. However, molecular …

Regeneration is a homeostatic process that involves the restoration of cells and body parts.
Most of the molecular mechanisms and signalling pathways involved in wound healing …

Pancreatic cancer (PanCa) is one of the leading causes of death from cancer in the United
States. The current standard treatment for pancreatic cancer is gemcitabine, but its success …