Meiotic recombination: the essence of heredity

N Hunter - Cold Spring Harbor perspectives in biology, 2015 - cshperspectives.cshlp.org
The study of homologous recombination has its historical roots in meiosis. In this context,
recombination occurs as a programmed event that culminates in the formation of crossovers …

Meiotic recombination in mammals: localization and regulation

F Baudat, Y Imai, B De Massy - Nature Reviews Genetics, 2013 - nature.com
During meiosis, a programmed induction of DNA double-strand breaks (DSBs) leads to the
exchange of genetic material between homologous chromosomes. These exchanges …

Control of meiotic crossovers: from double-strand break formation to designation

S Gray, PE Cohen - Annual review of genetics, 2016 - annualreviews.org
Meiosis, the mechanism of creating haploid gametes, is a complex cellular process
observed across sexually reproducing organisms. Fundamental to meiosis is the process of …

Meiotic recombination: mixing it up in plants

Y Wang, GP Copenhaver - Annual Review of Plant Biology, 2018 - annualreviews.org
Meiosis halves diploid chromosome numbers to haploid levels that are essential for sexual
reproduction in most eukaryotes. Meiotic recombination ensures the formation of bivalents …

Surfing the wave, cycle, life history, and genes/proteins expressed by testicular germ cells. Part 1: background to spermatogenesis, spermatogonia, and spermatocytes

L Hermo, RM Pelletier, DG Cyr… - … research and technique, 2010 - Wiley Online Library
Spermatogenesis, a study of germ cell development, is a long, orderly, and well‐defined
process occurring in seminiferous tubules of the testis. It is a temporal event whereby …

A SUMO-ubiquitin relay recruits proteasomes to chromosome axes to regulate meiotic recombination

HBDP Rao, H Qiao, SK Bhatt, LRJ Bailey, HD Tran… - Science, 2017 - science.org
Meiosis produces haploid gametes through a succession of chromosomal events, including
pairing, synapsis, and recombination. Mechanisms that orchestrate these events remain …

Natural variation and dosage of the HEI10 meiotic E3 ligase control Arabidopsis crossover recombination

PA Ziolkowski, CJ Underwood, C Lambing… - Genes & …, 2017 - genesdev.cshlp.org
During meiosis, homologous chromosomes undergo crossover recombination, which
creates genetic diversity and balances homolog segregation. Despite these critical …

[HTML][HTML] COSA-1 reveals robust homeostasis and separable licensing and reinforcement steps governing meiotic crossovers

R Yokoo, KA Zawadzki, K Nabeshima, M Drake, S Arur… - Cell, 2012 - cell.com
Crossovers (COs) between homologous chromosomes ensure their faithful segregation
during meiosis. We identify C. elegans COSA-1, a cyclin-related protein conserved in …

RNF212 is a dosage-sensitive regulator of crossing-over during mammalian meiosis

A Reynolds, H Qiao, Y Yang, JK Chen, N Jackson… - Nature …, 2013 - nature.com
Crossing-over ensures accurate chromosome segregation during meiosis, and every pair of
chromosomes obtains at least one crossover, even though the majority of recombination …

Crossing and zip**: molecular duties of the ZMM proteins in meiosis

A Pyatnitskaya, V Borde, A De Muyt - Chromosoma, 2019 - Springer
Accurate segregation of homologous chromosomes during meiosis depends on the ability of
meiotic cells to promote reciprocal exchanges between parental DNA strands, known as …