[HTML][HTML] Acetylcholinesterase inhibitors in the treatment of neurodegenerative diseases and the role of acetylcholinesterase in their pathogenesis

ŁJ Walczak-Nowicka, M Herbet - International journal of molecular …, 2021 - mdpi.com
Acetylcholinesterase (AChE) plays an important role in the pathogenesis of
neurodegenerative diseases by influencing the inflammatory response, apoptosis, oxidative …

Function of alternative splicing

S Stamm, S Ben-Ari, I Rafalska, Y Tang, Z Zhang… - Gene, 2005 - Elsevier
Alternative splicing is one of the most important mechanisms to generate a large number of
mRNA and protein isoforms from the surprisingly low number of human genes. Unlike …

Functional network analysis reveals extended gliomagenesis pathway maps and three novel MYC-interacting genes in human gliomas

M Bredel, C Bredel, D Juric, GR Harsh, H Vogel… - Cancer …, 2005 - aacrjournals.org
Gene expression profiling has proven useful in subclassification and outcome
prognostication for human glial brain tumors. The analysis of biological significance of the …

Acetylcholinesterase: a primary target for drugs and insecticides

S Thapa, M Lv, H Xu - Mini reviews in medicinal chemistry, 2017 - ingentaconnect.com
Background: Acetylcholinesterase is a serine hydrolase that terminates the action of the
neurotransmitter acetylcholine by hydrolyzing it into acetic acid and choline. Objective: The …

Linking pesticide exposure with pediatric leukemia: potential underlying mechanisms

AF Hernández, P Menéndez - International journal of molecular sciences, 2016 - mdpi.com
Leukemia is the most common cancer in children, representing 30% of all childhood
cancers. The disease arises from recurrent genetic insults that block differentiation of …

Termination and beyond: acetylcholinesterase as a modulator of synaptic transmission

G Zimmerman, H Soreq - Cell and tissue research, 2006 - Springer
Termination of synaptic transmission by neurotransmitter hydrolysis is a substantial
characteristic of cholinergic synapses. This unique termination mechanism makes …

Role of acetylcholinesterase in lung cancer

HJ **, RP Wu, JJ Liu, LJ Zhang, ZS Li - Thoracic cancer, 2015 - Wiley Online Library
Acetylcholinesterase (AChE) plays a key role in catalytic hydrolysis of cholinergic
neurotransmitters. Intensive research has proven the involvement of this protein in novel …

RUNX1 regulates migration, invasion, and angiogenesis via p38 MAPK pathway in human glioblastoma

K Sangpairoj, P Vivithanaporn, S Apisawetakan… - Cellular and molecular …, 2017 - Springer
Runt-related transcription factor 1 (RUNX1) is essential for the establishment of fetal and
adult hematopoiesis and neuronal development. Aberrant expression of RUNX1 led to …

Acetylcholinesterase and human cancers

SD Richbart, JC Merritt, NA Nolan… - Advances in Cancer …, 2021 - Elsevier
The enzyme acetylcholinesterase (AChE) is a serine hydrolase whose primary function is to
degrade acetylcholine (ACh) and terminate neurotransmission. Apart from its role in synaptic …

[HTML][HTML] Exposure to radio-frequency electromagnetic waves alters acetylcholinesterase gene expression, exploratory and motor coordination-linked behaviour in …

AO Obajuluwa, AJ Akinyemi, OB Afolabi, K Adekoya… - Toxicology reports, 2017 - Elsevier
Humans in modern society are exposed to an ever-increasing number of electromagnetic
fields (EMFs) and some studies have demonstrated that these waves can alter brain function …