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Wall shear stress and its role in atherosclerosis
M Zhou, Y Yu, R Chen, X Liu, Y Hu, Z Ma… - Frontiers in …, 2023 - frontiersin.org
Atherosclerosis (AS) is the major form of cardiovascular disease and the leading cause of
morbidity and mortality in countries around the world. Atherosclerosis combines the …
morbidity and mortality in countries around the world. Atherosclerosis combines the …
[HTML][HTML] Platelet secretion: From haemostasis to wound healing and beyond
EM Golebiewska, AW Poole - Blood reviews, 2015 - Elsevier
Upon activation, platelets secrete more than 300 active substances from their intracellular
granules. Platelet dense granule components, such as ADP and polyphosphates, contribute …
granules. Platelet dense granule components, such as ADP and polyphosphates, contribute …
Expert recommendations on the assessment of wall shear stress in human coronary arteries: existing methodologies, technical considerations, and clinical …
Expert recommendations on the assessment of wall shear stress in human coronary arteries:
existing methodologies, technical considerations, and clinical applications | European Heart …
existing methodologies, technical considerations, and clinical applications | European Heart …
Platelet biology and function: plaque erosion vs. rupture
The leading cause of heart disease in developed countries is coronary atherosclerosis,
which is not simply a result of ageing but a chronic inflammatory process that can lead to …
which is not simply a result of ageing but a chronic inflammatory process that can lead to …
New fundamentals in hemostasis
HH Versteeg, JWM Heemskerk, M Levi… - Physiological …, 2013 - journals.physiology.org
Hemostasis encompasses the tightly regulated processes of blood clotting, platelet
activation, and vascular repair. After wounding, the hemostatic system engages a plethora of …
activation, and vascular repair. After wounding, the hemostatic system engages a plethora of …
Deterministic lateral displacement: Challenges and perspectives
The advent of microfluidics in the 1990s promised a revolution in multiple industries from
healthcare to chemical processing. Deterministic lateral displacement (DLD) is a continuous …
healthcare to chemical processing. Deterministic lateral displacement (DLD) is a continuous …
Mechanical force-triggered drug delivery
Advanced drug delivery systems (DDS) enhance treatment efficacy of different therapeutics
in a dosage, spatial, and/or temporal controlled manner. To date, numerous chemical-or …
in a dosage, spatial, and/or temporal controlled manner. To date, numerous chemical-or …
Engineered in vitro disease models
The ultimate goal of most biomedical research is to gain greater insight into mechanisms of
human disease or to develop new and improved therapies or diagnostics. Although great …
human disease or to develop new and improved therapies or diagnostics. Although great …
Current and future antiplatelet therapies: emphasis on preserving haemostasis
Antiplatelet drugs, such as aspirin, P2Y12 antagonists, and glycoprotein (GP) IIb/IIIa
inhibitors, have proved to be successful in reducing the morbidity and mortality associated …
inhibitors, have proved to be successful in reducing the morbidity and mortality associated …
Shear-dependent platelet aggregation: mechanisms and therapeutic opportunities
A Rana, E Westein, B Niego… - Frontiers in cardiovascular …, 2019 - frontiersin.org
Cardiovascular diseases (CVD) are the number one cause of morbidity and death
worldwide. As estimated by the WHO, the global death rate from CVD is 31% wherein, a …
worldwide. As estimated by the WHO, the global death rate from CVD is 31% wherein, a …