MicroRNAs and exosomes: key players in HIV pathogenesis

J Sadri Nahand, F Bokharaei‐Salim… - HIV …, 2020 - Wiley Online Library
Objectives HIV infection is well known to cause impairment of the human immune system,
and until recently was a leading cause of death. It has been shown that T lymphocytes are …

Are microRNAs important players in HIV-1 infection? An update

M Balasubramaniam, J Pandhare, C Dash - Viruses, 2018 - mdpi.com
HIV-1 has already claimed over 35 million human lives globally. No curative treatments are
currently available, and the only treatment option for over 36 million people currently living …

NEAT1 long noncoding RNA and paraspeckle bodies modulate HIV-1 posttranscriptional expression

Q Zhang, CY Chen, VSRK Yedavalli, KT Jeang - MBio, 2013 - Am Soc Microbiol
Most of the human genome is transcribed into protein-noncoding RNAs (ncRNAs), including
small ncRNAs and long ncRNAs (lncRNAs). Over the past decade, rapidly emerging …

HIV-1 viral protein R activates NLRP3 inflammasome in microglia: implications for HIV-1 associated neuroinflammation

MK Mamik, E Hui, WG Branton, BA McKenzie… - Journal of Neuroimmune …, 2017 - Springer
Human Immunodeficiency virus (HIV) enters the brain soon after seroconversion and
induces chronic neuroinflammation by infecting and activating brain macrophages …

RNA viruses: RNA roles in pathogenesis, coreplication and viral load

P Poltronieri, B Sun, M Mallardo - Current genomics, 2015 - ingentaconnect.com
The review intends to present and recapitulate the current knowledge on the roles and
importance of regulatory RNAs, such as microRNAs and small interfering RNAs, RNA …

Lnc-ISG20 inhibits influenza A virus replication by enhancing ISG20 expression

W Chai, J Li, Q Shangguan, Q Liu, X Li, D Qi… - Journal of …, 2018 - Am Soc Microbiol
Long noncoding RNAs (lncRNAs) are involved in many aspects of cellular processes,
including the antiviral immune response. To identify influenza A virus (IAV)-related lncRNAs …

Host restriction factors in retroviral infection: promises in virus-host interaction

YH Zheng, KT Jeang, K Tokunaga - Retrovirology, 2012 - Springer
Retroviruses have an intricate life cycle. There is much to be learned from studying retrovirus-
host interactions. Among retroviruses, the primate lentiviruses have one of the more complex …

HibeRNAtion: HIV-1 RNA metabolism and viral latency

R Crespo, S Rao, T Mahmoudi - Frontiers in Cellular and Infection …, 2022 - frontiersin.org
HIV-1 infection remains non-curative due to the latent reservoir, primarily a small pool of
resting memory CD4+ T cells bearing replication-competent provirus. Pharmacological …

The effect of miRNA gene regulation on HIV disease

R Chinniah, T Adimulam, L Nandlal… - Frontiers in …, 2022 - frontiersin.org
Over many years, research on HIV/AIDS has advanced with the introduction of HAART.
Despite these advancements, significant gaps remain with respect to aspects in HIV life …

Non-coding RNAs in the etiology and control of major and neglected human tropical diseases

O Tamgue, CF Mezajou, NN Ngongang… - Frontiers in …, 2021 - frontiersin.org
Non-coding RNAs (ncRNAs) including microRNAs (miRs) and long non-coding RNAs
(lncRNAs) have emerged as key regulators of gene expression in immune cells …