Large animal models in regenerative medicine and tissue engineering: to do or not to do

I Ribitsch, PM Baptista, A Lange-Consiglio… - … in Bioengineering and …, 2020‏ - frontiersin.org
Rapid developments in Regenerative Medicine and Tissue Engineering has witnessed an
increasing drive toward clinical translation of breakthrough technologies. However, the …

Tendon tissue engineering: An overview of biologics to promote tendon healing and repair

V Citro, M Clerici, AR Boccaccini… - Journal of tissue …, 2023‏ - journals.sagepub.com
Tendons are dense connective tissues with a hierarchical polarized structure that respond to
and adapt to the transmission of muscle contraction forces to the skeleton, enabling motion …

Equine tendonitis therapy using mesenchymal stem cells and platelet concentrates: a randomized controlled trial

AM Carvalho, PR Badial, LEC Álvarez… - Stem cell research & …, 2013‏ - Springer
Introduction Tendon injury is a major cause of lameness and decreased performance in
athletic equines. Various therapies for tendonitis have been described; however, none of …

Regenerative medicine for the treatment of musculoskeletal overuse injuries in competition horses

P Torricelli, M Fini, G Filardo, M Tschon… - International …, 2011‏ - Springer
Purpose Tissue repair in musculoskeletal injuries is often a slow and sometimes incomplete
process. Regenerative medicine based on the use of growth factors (GFs) and cell therapy is …

Fetal derived embryonic-like stem cells improve healing in a large animal flexor tendonitis model

AE Watts, AE Yeager, OV Kopyov, AJ Nixon - Stem cell research & therapy, 2011‏ - Springer
Introduction Tendon injury is a common problem in athletes, with poor tissue regeneration
and a high rate of re-injury. Stem cell therapy is an attractive treatment modality as it may …

The roles and therapeutic potentialof mesenchymal stem/stromal cells and their extracellular vesicles in tendinopathies

D Quintero, C Perucca Orfei, LD Kaplan… - … in bioengineering and …, 2023‏ - frontiersin.org
Tendinopathies encompass a highly prevalent, multi-faceted spectrum of disorders,
characterized by activity-related pain, compromised function, and propensity for an extended …

A review on the use of cell therapy in the treatment of tendon disease and injuries

JOY Ho, P Sawadkar, V Mudera - Journal of Tissue …, 2014‏ - journals.sagepub.com
Tendon disease and injuries carry significant morbidity worldwide in both athletic and non-
athletic populations. It is estimated that tendon injuries account for 30%− 50% of all …

Mesenchymal stem cell-derived extracellular vesicles for the promotion of tendon repair-an update of literature

PPY Lui - Stem cell reviews and reports, 2021‏ - Springer
Tendon injuries are prevalent in physical activities and sports. Tendon heals slowly after
injuries. The results of conservative treatments and surgery are not satisfactory with high re …

Fibrin glue as the cell-delivery vehicle for mesenchymal stromal cells in regenerative medicine

X Wu, J Ren, J Li - Cytotherapy, 2012‏ - Elsevier
The use of tissue-engineering techniques such as stem-cell therapy to renew injured tissues
is a promising strategy in regenerative medicine. As a cell-delivery vehicle, fibrin glues (FG) …

Regenerative engineering of musculoskeletal tissues and interfaces

S Nukavarapu, J Freeman, C Laurencin - 2015‏ - books.google.com
Repair and regeneration of musculoskeletal tissues is generating substantial interest within
the biomedical community. Consequently, these are the most researched tissues from the …