Acinetobacter baumannii: Envelope Determinants That Control Drug Resistance, Virulence, and Surface Variability

E Geisinger, W Huo, J Hernandez-Bird… - Annual review of …, 2019 - annualreviews.org
Acinetobacter baumannii has emerged as an important nosocomial pathogen, particularly
for patients in intensive care units and with invasive indwelling devices. The most recent …

Interaction of antibacterial compounds with RND efflux pumps in Pseudomonas aeruginosa

J Dreier, P Ruggerone - Frontiers in microbiology, 2015 - frontiersin.org
Pseudomonas aeruginosa infections are becoming increasingly difficult to treat due to
intrinsic antibiotic resistance and the propensity of this pathogen to accumulate diverse …

A complex immune response to flagellin epitope variation in commensal communities

NR Colaianni, K Parys, HS Lee, JM Conway, NH Kim… - Cell Host & Microbe, 2021 - cell.com
Immune systems restrict microbial pathogens by identifying" non-self" molecules called
microbe-associated molecular patterns (MAMPs). It is unclear how immune responses are …

Resources for genetic and genomic analysis of emerging pathogen Acinetobacter baumannii

LA Gallagher, E Ramage, EJ Weiss… - Journal of …, 2015 - journals.asm.org
Acinetobacter baumannii is a Gram-negative bacterial pathogen notorious for causing
serious nosocomial infections that resist antibiotic therapy. Research to identify factors …

Contribution of resistance-nodulation-cell division efflux systems to antibiotic resistance and biofilm formation in Acinetobacter baumannii

EJ Yoon, Y Nait Chabane, S Goussard, E Snesrud… - MBio, 2015 - journals.asm.org
Acinetobacter baumannii is a nosocomial pathogen of increasing importance due to its
multiple resistance to antibiotics and ability to survive in the hospital environment linked to …

Substrate specificities and efflux efficiencies of RND efflux pumps of Acinetobacter baumannii

IV Leus, JW Weeks, V Bonifay, L Smith… - Journal of …, 2018 - journals.asm.org
Antibiotic-resistant Acinetobacter baumannii causes infections that are extremely difficult to
treat. A significant role in these resistance profiles is attributed to multidrug efflux pumps …

The Acinetobacter baumannii two-component system AdeRS regulates genes required for multidrug efflux, biofilm formation, and virulence in a strain-specific manner

GE Richmond, LP Evans, MJ Anderson, ME Wand… - MBio, 2016 - journals.asm.org
The opportunistic pathogen Acinetobacter baumannii is able to persist in the environment
and is often multidrug resistant (MDR), causing difficulties in the treatment of infections …

A Potential Combination Therapy of Berberine Hydrochloride With Antibiotics Against Multidrug-Resistant Acinetobacter baumannii

X Li, Y Song, L Wang, G Kang, P Wang… - Frontiers in Cellular …, 2021 - frontiersin.org
Multidrug-resistant (MDR) Acinetobacter baumannii strains can cause severe infections in
intensive care units, and are rapidly develo** resistance to the last-resort of existing …

Biofilm-associated proteins: news from Acinetobacter

E De Gregorio, M Del Franco, M Martinucci, E Roscetto… - BMC genomics, 2015 - Springer
Background A giant protein called BAP (biofilm-associated protein) plays a role in biofilm
formation and adhesion to host cells in A. baumannii. Most of the protein is made by arrays …

Mutation in the two-component regulator BaeSR mediates cefiderocol resistance and enhances virulence in Acinetobacter baumannii

X Liu, Y Chang, Q Xu, W Zhang, Z Huang, L Zhang… - Msystems, 2023 - journals.asm.org
Acinetobacter baumannii has become one of the most challenging pathogens in many
countries with limited treatment options available. Cefiderocol, a novel siderophore …