Pirfenidone, initially indicated for lung fibrosis, has gone beyond its original purpose, and
shown promise in eye care. This detailed review tracks its evolution from lung treatment to …

Ocular drug delivery is constrained by anatomical and physiological barriers, necessitating
innovative solutions for effective therapy. Natural polymers like hyaluronic acid, chitosan …

Fungal keratitis (FK) is recognized as a stubborn ocular condition, caused by intense fungal
invasiveness and heightened immune reaction. The glycosaminoglycan chondroitin sulfate …

Colloidal drug aggregates (CDAs) are challenging in drug discovery due to their
unpredictable formation and interference with screening assays. These limitations are …

In the present scenario, clinical success of all existing antimicrobial regimes has been
severely challenged by bacterial infections and emergence of multidrug-resistant strains …

The critical and unmet medical need for novel therapeutic advancements in the treatment of
age-related macular degeneration (AMD) cannot be overstated, particularly given the aging …

Purpose Patients afflicted with dry eye disease (DED) experience significant discomfort. The
underlying cause of DED is the excessive accumulation of ROS on the ocular surface. Here …

In this study, we aimed to develop ion-responsive and biocompatible alginate-capped
nanoceria (Ce-ALG) for β-1, 3-glucan (ie, wound healing agent) delivery and corneal …

Diabetic wounds are characterized by chronic trauma, with long-term non-healing attributed
to persistent inflammation and recurrent bacterial infections. Exacerbation of the …

Corneal neovascularization (CNV) is one of the common blinding factors worldwide, leading
to reduced vision or even blindness. However, current treatments such as surgical …