Pathological alterations to the locus coeruleus, the major source of noradrenaline in the
brain, are histologically evident in early stages of neurodegenerative diseases. Novel MRI …

Dopamine is a neurotransmitter that is produced in the substantia nigra, ventral tegmental
area, and hypothalamus of the brain. Dysfunction of the dopamine system has been …

Protective role of apigenin on rotenone induced rat model of Parkinson's disease: Suppression of
neuroinflammation and oxidative stress mediated apoptosis - ScienceDirect Skip to main …

Alzheimer's disease (AD) and Parkinson's disease (PD) are the two most widespread
neurological disorders (NDs) characterized by degeneration of cognitive and motor …

Research in the last decade strongly suggests that mesenchymal stem cell (MSC)-mediated
therapeutic benefits are mainly due to their secretome, which has been proposed as a …

Background Parkinson's disease (PD) is a neurodegenerative disorder involving the
degeneration of dopaminergic neurons in the substantia nigra pars compacta (SNpc) …

Our understanding of the role of innate and adaptive immune cell function in brain health
and how it goes awry during aging and neurodegenerative diseases is still in its infancy …

The degeneration of dopaminergic neurons is a major contributor to the pathogenesis of mid‐
brain disorders. Clinically, cell therapeutic solutions, by increasing the neurotransmitter …

3-3s represent a family of highly conserved 30 kDa acidic proteins. 14-3-3s recognize and
bind specific phospho-sequences on client partners and operate as molecular hubs to …

Creatine is widely used by both elite and recreational athletes as an ergogenic aid to
enhance anaerobic exercise performance. Older individuals also use creatine to prevent …