Map** current research and identifying hotspots on mesenchymal stem cells in cardiovascular disease

C Chen, Y Lou, XY Li, ZT Lv, LQ Zhang… - Stem Cell Research & …, 2020 - Springer
Abstract Background Mesenchymal stem cells (MSCs) have important research value and
broad application prospects in the cardiovascular disease. This study provides information …

Nicorandil: a drug with ongoing benefits and different mechanisms in various diseased conditions

LA Ahmed - Indian Journal of Pharmacology, 2019 - journals.lww.com
Nicorandil is a well-known antianginal agent, which has been recommended as one of the
second-line treatments for chronic stable angina as justified by the European guidelines. It …

Canagliflozin attenuates isoprenaline-induced cardiac oxidative stress by stimulating multiple antioxidant and anti-inflammatory signaling pathways

R Hasan, S Lasker, A Hasan, F Zerin, M Zamila… - Scientific reports, 2020 - nature.com
The antidiabetic drug canagliflozin is reported to possess several cardioprotective effects.
However, no studies have investigated protective effects of canagliflozin in isoprenaline …

Canagliflozin ameliorates renal oxidative stress and inflammation by stimulating AMPK–Akt–eNOS pathway in the isoprenaline-induced oxidative stress model

R Hasan, S Lasker, A Hasan, F Zerin, M Zamila… - Scientific Reports, 2020 - nature.com
Diabetes is a leading cause of chronic kidney disease, and the high prevalence of
sympathetic nervous system (SNS) hyperactivity in diabetic patients makes them further …

Nicorandil-Pretreated Mesenchymal Stem Cell-Derived Exosomes Facilitate Cardiac Repair After Myocardial Infarction via Promoting Macrophage M2 Polarization by …

ZT Gong, YY **ong, Y Ning, RJ Tang… - International Journal …, 2024 - Taylor & Francis
Background Exosomes derived from bone marrow mesenchymal stem cells (MSC-exo) have
been considered as a promising cell-free therapeutic strategy for ischemic heart disease …

Activated ROCK/Akt/eNOS and ET-1/ERK pathways in 5-fluorouracil-induced cardiotoxicity: modulation by simvastatin

RN Muhammad, N Sallam, HS El-Abhar - Scientific reports, 2020 - nature.com
Fluorouracil (5-FU) is used in the treatment of different solid tumors; however, its use is
associated with rare, but serious cardiotoxicity. Nevertheless, the involvement of ROCK/NF …

Modulatory effect of rupatadine on mesenchymal stem cell-derived exosomes in hepatic fibrosis in rats: a potential role for miR-200a

MA Didamoony, AM Atwa, LA Ahmed - Life sciences, 2023 - Elsevier
Aims Mesenchymal stem cell-derived exosomes (MSC-EXOs) have emerged as a promising
approach in regenerative medicine for management of different diseases. However, the …

Enrichment of alpha-linolenic acid in rodent diet reduced oxidative stress and inflammation during myocardial infarction

KS Leung, JM Galano, C Oger, T Durand… - Free Radical Biology and …, 2021 - Elsevier
Myocardial infarction (MI) is an irreversible event caused by cardiac ischemia and may be
fatal. Studies reported that increased intake of n-3 polyunsaturated fatty acids (PUFA) …

[HTML][HTML] Enhancers of mesenchymal stem cell stemness and therapeutic potency

M Al-Azab, E Idiiatullina, M Safi, K Hezam - Biomedicine & …, 2023 - Elsevier
Mesenchymal stem cells (MSCs) are multipotent stromal cells that can differentiate into a
range of cell types, including osteoblasts, chondrocytes, myocytes, and adipocytes. Multiple …

Lercanidipine boosts the efficacy of mesenchymal stem cell therapy in 3-NP-induced Huntington's disease model rats via modulation of the calcium/calcineurin …

EM Elbaz, HS Helmy, AE El-Sahar, MA Saad… - Neurochemistry …, 2019 - Elsevier
Nitropropionic acid (3-NP) induces a spectrum of Huntington's disease (HD)-like
neuropathologies in the rat striatum. The present study aimed to demonstrate the …