Modifiable risk factors for Alzheimer's disease

GA Edwards III, N Gamez, G Escobedo Jr… - Frontiers in aging …, 2019 - frontiersin.org
Since first described in the early 1900s, Alzheimer's disease (AD) has risen exponentially in
prevalence and concern. Research still drives to understand the etiology and pathogenesis …

[HTML][HTML] Obstructive sleep apnea and its treatment in aging: effects on Alzheimer's disease biomarkers, cognition, brain structure and neurophysiology

AE Mullins, K Kam, A Parekh, OM Bubu, RS Osorio… - Neurobiology of …, 2020 - Elsevier
Here we review the impact of obstructive sleep apnea (OSA) on biomarkers of Alzheimer's
disease (AD) pathogenesis, neuroanatomy, cognition and neurophysiology, and present the …

Sleep and longitudinal cognitive performance in preclinical and early symptomatic Alzheimer's disease

BP Lucey, J Wisch, AH Boerwinkle, EC Landsness… - Brain, 2021 - academic.oup.com
Sleep monitoring may provide markers for future Alzheimer's disease; however, the
relationship between sleep and cognitive function in preclinical and early symptomatic …

CCCDTD5 recommendations on early non cognitive markers of dementia: A Canadian consensus

M Montero‐Odasso, F Pieruccini‐Faria… - … Research & Clinical …, 2020 - Wiley Online Library
Introduction Cognitive impairment is the hallmark of Alzheimer's disease (AD) and related
dementias. However, motor decline has been recently described as a prodromal state that …

Role of sleep in neurodegeneration: the consensus report of the 5th Think Tank World Sleep Forum

L Ferini-Strambi, C Liguori, BP Lucey, BA Mander… - Neurological …, 2024 - Springer
Sleep abnormalities may represent an independent risk factor for neurodegeneration. An
international expert group convened in 2021 to discuss the state-of-the-science in this …

[HTML][HTML] Sleep in normal aging, homeostatic and circadian regulation and vulnerability to sleep deprivation

J Taillard, C Gronfier, S Bioulac, P Philip, P Sagaspe - Brain sciences, 2021 - mdpi.com
In the context of geriatric research, a growing body of evidence links normal age-related
changes in sleep with many adverse health outcomes, especially a decline in cognition in …

Impact of obstructive sleep apnea on cognitive and motor functions in Parkinson's disease

M Elfil, EI Bahbah, MM Attia, M Eldokmak… - Movement …, 2021 - Wiley Online Library
Introduction Parkinson's disease (PD) is a chronic neurodegenerative disorder that presents
with motor and non‐motor manifestations. Amongst the non‐motor features, various forms of …

Alterations of sleep oscillations in Alzheimer's disease: a potential role for GABAergic neurons in the cortex, hippocampus, and thalamus

F Katsuki, D Gerashchenko, RE Brown - Brain research bulletin, 2022 - Elsevier
Sleep abnormalities are widely reported in patients with Alzheimer's disease (AD) and are
linked to cognitive impairments. Sleep abnormalities could be potential biomarkers to detect …

Sleep spindle abnormalities related to Alzheimer's disease: a systematic mini-review

YY Weng, X Lei, J Yu - Sleep medicine, 2020 - Elsevier
Accumulating evidence supports a bidirectional relationship between sleep disruption and
Alzheimer's disease (AD) pathology. Among various sleep electroencephalography …

[HTML][HTML] Preoperative recovery sleep ameliorates postoperative cognitive dysfunction aggravated by sleep fragmentation in aged mice by enhancing Eeg Delta-wave …

Y Li, S Hou, F Li, S Long, Y Yang, Y Li, L Zhao… - Brain Research …, 2024 - Elsevier
Sleep fragmentation (SF) is a common sleep problem experienced during the perioperative
period by older adults, and is associated with postoperative cognitive dysfunction (POCD) …