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Shining new light on biological systems: luminescent transition metal complexes for bioimaging and biosensing applications
Luminescence imaging is a powerful and versatile technique for investigating cell
physiology and pathology in living systems, making significant contributions to life science …
physiology and pathology in living systems, making significant contributions to life science …
[HTML][HTML] Amyloid β, Tau, and α-Synuclein aggregates in the pathogenesis, prognosis, and therapeutics for neurodegenerative diseases
Aggregation of specific proteins are histopathological hallmarks of several
neurodegenerative diseases, such as, Amyloid β (Aβ) plaques and tau neurofibrillary …
neurodegenerative diseases, such as, Amyloid β (Aβ) plaques and tau neurofibrillary …
Biomolecular condensates at the nexus of cellular stress, protein aggregation disease and ageing
Biomolecular condensates are membraneless intracellular assemblies that often form via
liquid− liquid phase separation and have the ability to concentrate biopolymers. Research …
liquid− liquid phase separation and have the ability to concentrate biopolymers. Research …
The proteostasis network and its decline in ageing
Ageing is a major risk factor for the development of many diseases, prominently including
neurodegenerative disorders such as Alzheimer disease and Parkinson disease. A hallmark …
neurodegenerative disorders such as Alzheimer disease and Parkinson disease. A hallmark …
Ageing exacerbates ribosome pausing to disrupt cotranslational proteostasis
Ageing is accompanied by a decline in cellular proteostasis, which underlies many age-
related protein misfolding diseases,. Yet, how ageing impairs proteostasis remains unclear …
related protein misfolding diseases,. Yet, how ageing impairs proteostasis remains unclear …
Inflammasomes as therapeutic targets in human diseases
Y Li, H Huang, B Liu, Y Zhang, X Pan, XY Yu… - Signal transduction and …, 2021 - nature.com
Inflammasomes are protein complexes of the innate immune system that initiate
inflammation in response to either exogenous pathogens or endogenous danger signals …
inflammation in response to either exogenous pathogens or endogenous danger signals …
Food protein amyloid fibrils: Origin, structure, formation, characterization, applications and health implications
Amyloid fibrils have traditionally been considered only as pathological aggregates in human
neurodegenerative diseases, but it is increasingly becoming clear that the propensity to form …
neurodegenerative diseases, but it is increasingly becoming clear that the propensity to form …
Amyloid nomenclature 2018: recommendations by the International Society of Amyloidosis (ISA) nomenclature committee
The nomenclature committee of the International Society of Amyloidosis (ISA) meets every
second year to discuss and formulate recommendations. The conclusions from the …
second year to discuss and formulate recommendations. The conclusions from the …
Protein-stabilized Pickering emulsions: Formation, stability, properties, and applications in foods
X Yan, C Ma, F Cui, DJ McClements, X Liu… - Trends in Food Science & …, 2020 - Elsevier
Background Pickering emulsions prepared using food-grade colloidal particles can be
designed to have high physical stability, tunable textural attributes, and good …
designed to have high physical stability, tunable textural attributes, and good …
Amyloid-type protein aggregation and prion-like properties of amyloids
This review will focus on the process of amyloid-type protein aggregation. Amyloid fibrils are
an important hallmark of protein misfolding diseases and therefore have been investigated …
an important hallmark of protein misfolding diseases and therefore have been investigated …