Exploring the potential of bioactive peptides: From natural sources to therapeutics

K Purohit, N Reddy, A Sunna - International Journal of Molecular …, 2024 - mdpi.com
Bioactive peptides, specific protein fragments with positive health effects, are gaining
traction in drug development for advantages like enhanced penetration, low toxicity, and …

Peptides as “better biomarkers”? Value, challenges, and potential solutions to facilitate implementation

A Latosinska, M Frantzi, J Siwy - Mass spectrometry reviews, 2024 - Wiley Online Library
Peptides carry important functions in normal physiological and pathophysiological
processes and can serve as clinically useful biomarkers. Given the ability to diffuse …

Goat milk-derived short chain peptides: Peptide LPYV as species-specific characteristic and their versatility bioactivities by MOF@ Fe3O4@ GO mesoporous magnetic …

W Jia, A Du, Z Fan, L Shi - Food Research International, 2023 - Elsevier
Goat milk as an ideal substitute for human milk has not been sufficiently explored. An in-situ
synthesized MOF@ Fe 3 O 4@ GO was demonstrated as a magnetic mesoporous adsorbent …

Comprehensive identification of short and medium-sized peptides from pixian broad bean paste protein hydrolysates using UPLC-Q–TOF–MS and UHPLC-Q exactive …

M Li, W Fan, Y Xu - Journal of Agricultural and Food Chemistry, 2022 - ACS Publications
Pixian broad bean paste (PBBP) is an indispensable food widely used in many East Asian
countries, yet the knowledge about bioactive peptides released from parent proteins by …

Isolation and functional characterization of hemp seed protein-derived short-and medium-chain peptide mixtures with multifunctional properties for metabolic …

A Cerrato, C Lammi, AL Capriotti, C Bollati… - Food Research …, 2023 - Elsevier
This study aims to obtain a valuable mixture of short-chain peptides from hempseed as a
new ingredient for develo** nutraceutical and functional foods useful for preventing …

Effects of short-chain peptides on the flavor profile of baijiu by the density functional theory: Peptidomics, sensomics, flavor reconstitution, and sensory evaluation

W Jia, A Du, Z Fan, Y Wang, L Shi - Journal of Agricultural and …, 2022 - ACS Publications
The effect of peptides on the flavor profile of Baijiu is unclear as a result of their trace
concentrations in the complex matrix, and therefore, the study involving the interaction …

Peptidomics as a tool to analyze endogenous peptides in milk and milk-related peptides

J Ning, M Li, W Chen, H Zhao, J Chen, M Yang, X Cao… - Food Bioscience, 2022 - Elsevier
As a subset of the proteome, peptidomics is the best tool to analyze peptides in different food
matrices. Milk peptides are produced by protease hydrolysis in the mammary gland, which …

[HTML][HTML] A multi-centre peptidomics investigation of food digesta: current state of the art in mass spectrometry analysis and data visualisation

R Portmann, P Jiménez-Barrios, J Jardin… - Food Research …, 2023 - Elsevier
Mass spectrometry has become the technique of choice for the assessment of a high variety
of molecules in complex food matrices. It is best suited for monitoring the evolution of …

Peptidomic analyses: The progress in enrichment and identification of endogenous peptides

J Peng, H Zhang, H Niu - TrAC trends in analytical chemistry, 2020 - Elsevier
Peptidomics is the comprehensive profiling of endogenous peptides from the biological
sources. As with genome, transcriptome, proteome and metabolome, the peptidome is …

Mass spectrometry in the discovery of peptides involved in intercellular communication: From targeted to untargeted peptidomics approaches

KT Fan, CW Hsu, YR Chen - Mass Spectrometry Reviews, 2023 - Wiley Online Library
Endogenous peptide hormones represent an essential class of biomolecules, which
regulate cell–cell communications in diverse physiological processes of organisms. Mass …