Mechanisms, applications, and challenges of insect RNA interference

KY Zhu, SR Palli - Annual review of entomology, 2020 - annualreviews.org
The RNA interference (RNAi) triggered by short/small interfering RNA (siRNA) was
discovered in nematodes and found to function in most living organisms. RNAi has been …

Double-stranded RNA technology to control insect pests: current status and challenges

O Christiaens, S Whyard, AM Vélez… - Frontiers in Plant …, 2020 - frontiersin.org
Exploiting the RNA interference (RNAi) gene mechanism to silence essential genes in pest
insects, leading to toxic effects, has surfaced as a promising new control strategy in the past …

Visualization of the process of a nanocarrier-mediated gene delivery: stabilization, endocytosis and endosomal escape of genes for intracellular spreading

Z Ma, Y Zheng, Z Chao, H Chen, Y Zhang… - Journal of …, 2022 - Springer
Nanoparticles have been widely applied as gene carrier for improving RNA interference
(RNAi) efficiency in medical and agricultural fields. However, the mechanism and delivery …

Molecular mechanisms influencing efficiency of RNA interference in insects

AMW Cooper, K Silver, J Zhang, Y Park… - Pest management …, 2019 - Wiley Online Library
RNA interference (RNAi) is an endogenous, sequence‐specific gene‐silencing mechanism
elicited by small RNA molecules. RNAi is a powerful reverse genetic tool, and is currently …

[HTML][HTML] RNA-based technologies for insect control in plant production

S Liu, M Jaouannet, DMA Dempsey, J Imani… - Biotechnology …, 2020 - Elsevier
RNA interference (RNAi) is a biological process in which small RNA (sRNA) molecules
sequence-specifically silence gene expression at the transcriptional or post-transcriptional …

RNAi-based pest control: Production, application and the fate of dsRNA

L He, Y Huang, X Tang - Frontiers in Bioengineering and …, 2022 - frontiersin.org
The limitations of conventional pesticides have raised the demand for innovative and
sustainable solutions for plant protection. RNA Interference (RNAi) triggered by dsRNA has …

RNA interference in insects: protecting beneficials and controlling pests

E Vogel, D Santos, L Mingels, TW Verdonckt… - Frontiers in …, 2019 - frontiersin.org
Insects constitute the largest and most diverse group of animals on Earth with an equally
diverse virome. The main antiviral immune system of these animals is the post …

A first greenhouse application of bacteria-expressed and nanocarrier-delivered RNA pesticide for Myzus persicae control

Z Ma, Y Zhang, M Li, Z Chao, X Du, S Yan… - Journal of Pest Science, 2023 - Springer
There are two main limitations for sprayable RNA pesticide development: delivery efficiency
and synthetic cost of double-stranded RNA (dsRNA). We previously constructed a …

[PDF][PDF] Nanoparticle-based nontransformative RNA insecticides for sustainable pest control: Mechanisms, current status and challenges

S Yan, MZ Yin, J Shen - Entomol. Gen, 2022 - researchgate.net
RNA interference (RNAi) described as post transcriptional gene silencing offers great
opportunities for develo** RNA insecticide for sustainable pest management. In the past …

RNAi turns 25: contributions and challenges in insect science

SR Palli - Frontiers in Insect Science, 2023 - frontiersin.org
Since its discovery in 1998, RNA interference (RNAi), a Nobel prize-winning technology,
made significant contributions to advances in biology because of its ability to mediate the …