Thrombosis is a major complication of cardiovascular disease, leading to myocardial
infarction, acute ischemic stroke, or venous thromboembolism. Thrombosis occurs when a …

Multiple mechanisms mediate thrombin generation and consequently the thrombin
concentration present during fibrin formation. First, the levels of pro-and anticoagulants …

Although arterial and venous thromboembolic disorders are among the most frequent
causes of mortality and morbidity, there has been little description of how the composition of …

New evidence has stirred up a long‐standing but undeservedly forgotten interest in the role
of erythrocytes, or red blood cells (RBCs), in blood clotting and its disorders. This review …

Red blood cells (RBCs) have historically been considered passive bystanders in
thrombosis. However, clinical and epidemiological studies have associated quantitative and …

Venous thromboembolism (VTE) encompasses deep-vein thrombosis (DVT) and pulmonary
embolism. VTE is the leading cause of lost disability-adjusted life years and the third leading …

In response to vessel injury (or other pathological conditions), the hemostatic process is
activated, resulting in a fibrous, cellular-rich structure commonly referred to as a blood clot …

In contrast to an obsolete notion that erythrocytes, or red blood cells (RBC s), play a passive
and minor role in haemostasis and thrombosis, over the past decades there has been …

While hemostasis is the physiological process that prevents blood loss after vessel injury,
thrombosis is often portrayed as a pathologic event involving blood coagulation and platelet …

Fibrinolysis appears in many diverse physiological situations, and the components of the
system are well established, along with mechanistic details for the individual reactions and …