Microbiota in health and diseases

K Hou, ZX Wu, XY Chen, JQ Wang, D Zhang… - Signal transduction and …, 2022 - nature.com
The role of microbiota in health and diseases is being highlighted by numerous studies
since its discovery. Depending on the localized regions, microbiota can be classified into …

Colonization, Infection, and the Accessory Genome of Klebsiella pneumoniae

RM Martin, MA Bachman - Frontiers in cellular and infection …, 2018 - frontiersin.org
Klebsiella pneumoniae is a Gram-negative pathogen that has a large accessory genome of
plasmids and chromosomal gene loci. This accessory genome divides K. pneumoniae …

Biology of Acinetobacter baumannii: Pathogenesis, Antibiotic Resistance Mechanisms, and Prospective Treatment Options

CR Lee, JH Lee, M Park, KS Park, IK Bae… - Frontiers in cellular …, 2017 - frontiersin.org
Acinetobacter baumannii is undoubtedly one of the most successful pathogens responsible
for hospital-acquired nosocomial infections in the modern healthcare system. Due to the …

The evolution and ecology of bacterial warfare

ET Granato, TA Meiller-Legrand, KR Foster - Current biology, 2019 - cell.com
Bacteria have evolved a wide range of mechanisms to harm and kill their competitors,
including chemical, mechanical and biological weapons. Here we review the incredible …

Understanding competition and cooperation within the mammalian gut microbiome

KZ Coyte, S Rakoff-Nahoum - Current Biology, 2019 - cell.com
The mammalian gut harbors a vast community of microorganisms—termed the microbiota—
whose composition and dynamics are considered to be critical drivers of host health. These …

Secretion systems in Gram-negative bacteria: structural and mechanistic insights

TRD Costa, C Felisberto-Rodrigues, A Meir… - Nature Reviews …, 2015 - nature.com
Bacteria have evolved a remarkable array of sophisticated nanomachines to export various
virulence factors across the bacterial cell envelope. In recent years, considerable progress …

Genomic and Metabolic Characteristics of the Pathogenicity in Pseudomonas aeruginosa

T De Sousa, M Hébraud, MLNE Dapkevicius… - International journal of …, 2021 - mdpi.com
In recent years, the effectiveness of antimicrobials in the treatment of Pseudomonas
aeruginosa infections has gradually decreased. This pathogen can be observed in several …

Interference in bacterial quorum sensing: a biopharmaceutical perspective

B Rémy, S Mion, L Plener, M Elias… - Frontiers in …, 2018 - frontiersin.org
Numerous bacteria utilize molecular communication systems referred to as quorum sensing
(QS) to synchronize the expression of certain genes regulating, among other aspects, the …

The Type VI secretion system: a versatile bacterial weapon

S Coulthurst - Microbiology, 2019 - microbiologyresearch.org
The Type VI secretion system (T6SS) is a protein nanomachine that is widespread in Gram-
negative bacteria and is used to translocate effector proteins directly into neighbouring cells …

Aim, load, fire: the type VI secretion system, a bacterial nanoweapon

FR Cianfanelli, L Monlezun, SJ Coulthurst - Trends in microbiology, 2016 - cell.com
Bacteria utilise specialised protein secretion systems to interact with host organisms,
competitor bacteria, and the environment. The Type VI secretion system (T6SS) is a versatile …