[HTML][HTML] Challenges and opportunities in modelling wet granulation in pharmaceutical industry–a critical review

M Singh, S Shirazian, V Ranade, GM Walker… - Powder Technology, 2022 - Elsevier
Wet granulation is a key step in the pharmaceutical manufacturing of solid-dosage forms.
Wet granulation is used in pharmaceutical production to enhance formulation qualities such …

Challenges and opportunities concerning numerical solutions for population balances: a critical review

M Singh, V Ranade, O Shardt… - Journal of Physics A …, 2022 - iopscience.iop.org
Population balance models are tools for the study of dispersed systems, such as granular
materials, polymers, colloids and aerosols. They are applied with increasing frequency …

DEM–CFD modeling of a fluidized bed spray granulator

L Fries, S Antonyuk, S Heinrich, S Palzer - Chemical Engineering Science, 2011 - Elsevier
Coupled DEM–CFD simulations have been performed to study the fluid and particle
dynamics in a fluidized bed spray granulator on the scale of individual particles. The aim of …

[BOK][B] Analytic Methods for Coagulation-Fragmentation Models, Volume I

J Banasiak, W Lamb, P Laurençot - 2019 - taylorfrancis.com
Analytic Methods for Coagulation-Fragmentation Models is a two-volume set that provides a
comprehensive exposition of the mathematical analysis of coagulation-fragmentation …

Crystal population balance formulation and solution methods: a review

HM Omar, S Rohani - Crystal Growth & Design, 2017 - ACS Publications
Crystallization is an important part of many chemical industries. Efforts are being invested to
improve the performance of the crystallization process by designing novel crystallizers. An …

Model-based analysis of high shear wet granulation from batch to continuous processes in pharmaceutical production–a critical review

A Kumar, KV Gernaey, T De Beer, I Nopens - European Journal of …, 2013 - Elsevier
The manufacturing of pharmaceutical dosage forms, which has traditionally been a batch-
wise process, is now also transformed into a series of continuous operations. Some …

Solution of population balance equations in applications with fine particles: mathematical modeling and numerical schemes

TT Nguyen, F Laurent, RO Fox, M Massot - Journal of Computational …, 2016 - Elsevier
The accurate description and robust simulation, at relatively low cost, of global quantities (eg
number density or volume fraction) as well as the size distribution of a population of fine …

Numerical methods for the solution of population balance equations coupled with computational fluid dynamics

M Shiea, A Buffo, M Vanni… - Annual review of …, 2020 - annualreviews.org
This review article discusses the solution of population balance equations, for the simulation
of disperse multiphase systems, tightly coupled with computational fluid dynamics. Although …

Laplace transform‐based approximation methods for solving pure aggregation and breakage equations

S Kaushik, S Hussain, R Kumar - Mathematical Methods in the …, 2023 - Wiley Online Library
The varied applications of the aggregation and breakage equations in several fields of
science have attracted many researchers to explore accurate novel methods to calculate …

Dynamic simulation of emulsion formation in a high pressure homogenizer

A Håkansson, C Trägårdh, B Bergenståhl - Chemical Engineering Science, 2009 - Elsevier
A simulation model for emulsification in high pressure homogenization (HPH), based on a
population balance approach, is developed assuming it to be controlled by three …