An updated review on the genetics of primary open angle glaucoma

K Abu-Amero, AA Kondkar, KV Chalam - International journal of …, 2015 - mdpi.com
Epidemiological studies suggest that by 2020 the prevalence of primary open angle
glaucoma (POAG) is estimated to increase to 76.0 million, and to 111.8 million by 2040 …

The genetic mechanisms of primary angle closure glaucoma

DF Ahram, WL Alward, MH Kuehn - Eye, 2015 - nature.com
Abstract Primary Angle Closure Glaucoma (PACG) is one of the most common types of
glaucoma affecting over 15 million individuals worldwide. Family history and ethnicity are …

Association of gene polymorphisms with primary open angle glaucoma: a systematic review and meta-analysis

M Chen, X Yu, J Xu, J Ma, X Chen… - … & visual science, 2019 - iovs.arvojournals.org
Methods: We searched in PubMed and Web of Science (up to January 10, 2018) for genetic
studies of POAG. All case control studies investigating the association between single …

Current understanding of genetics and epigenetics in pseudoexfoliation syndrome and glaucoma

RS Kapuganti, DP Alone - Molecular Aspects of Medicine, 2023 - Elsevier
Pseudoexfoliation is a complex, progressive, and systemic age-related disorder. The early
stage of deposition of extracellular fibrillar material on ocular and extraocular tissues is …

COL18A1 is a candidate eye iridocorneal angle-closure gene in humans

F Suri, S Yazdani, M Chapi, I Safari… - Human molecular …, 2018 - academic.oup.com
Primary angle-closure glaucoma (PACG) is a common form of glaucoma in the Far East. Its
defining feature is iridocorneal angle closure. In addition to PACG, indications of angle …

Genetics of exfoliation syndrome and glaucoma

IF Aboobakar, RR Allingham - International ophthalmology clinics, 2014 - journals.lww.com
Glaucoma refers to a heterogenous group of disorders that are characterized by progressive
loss of retinal ganglion cells and visual field loss. 1 It is the leading cause of irreversible …

Association of the methylenetetrahydrofolate reductase (MTHFR) C677T polymorphism with primary glaucoma in Saudi population

H Al-Shahrani, N Al-Dabbagh, N Al-Dohayan… - BMC …, 2016 - Springer
Background Methylenetetrahydrofolate reductase (MTHFR), a critical enzyme in folate
metabolism is involved in DNA synthesis, DNA repair and DNA methylation. The functional …

Association between MTHFR C677T polymorphism and primary open-angle glaucoma: A meta-analysis

Y Huo, H Zou, M Lang, SX Ji, XL Yin, Z Zheng, W Liu… - Gene, 2013 - Elsevier
Epidemiological studies have evaluated the association between methylenetetrahydrofolate
reductase (MTHFR) C677T polymorphism and primary open-angle glaucoma (POAG) risk …

Clinical and laboratory biomarkers for pseudoexfoliation syndrome

K Kamel, L Bourke, C O'Brien - Journal of Glaucoma, 2018 - journals.lww.com
Clinical and Laboratory Biomarkers for Pseudoexfoliation Syn... : Journal of Glaucoma Clinical
and Laboratory Biomarkers for Pseudoexfoliation Syndrome : Journal of Glaucoma Log in or …

[HTML][HTML] Association of MTHFR C677T and A1298C polymorphisms with glaucoma risk: a systematic review Meta-analysis based 42 case-control studies

M Gohari, SA Mirjalili, MJ Akbarian-Bafghi… - Romanian journal of …, 2019 - ncbi.nlm.nih.gov
Aim: Several epidemiological studies have been performed to explore the association of
MTHFR polymorphisms with glaucoma risk. However, the results were inconsistent or even …