Cancer accounted for 7.6 million deaths (around 13% of all deaths) worldwide in 2008.(1)
Almost 13 million cancer cases are newly diagnosed every year, and deaths are projected to …

The development of multifunctional agents for simultaneous tumor targeting and near
infrared (NIR) fluorescence imaging is expected to have significant impact on future …

A recent metaanalysis shows that 0.7% of nanoparticles are delivered to solid tumors. This
low delivery efficiency has major implications in the translation of cancer nanomedicines, as …

Many modalities of cancer therapy induce mechanisms of treatment resistance and escape
pathways during chronic treatments, including photodynamic therapy (PDT). It is …

Photodynamic therapy (PDT) is a promising treatment strategy where activation of
photosensitizer drugs with specific wavelengths of light results in energy transfer cascades …

Theranostics, the fusion of therapy and diagnostics for optimizing efficacy and safety of
therapeutic regimes, is a growing field that is paving the way towards the goal of …

Abstract Bee venom (BV)(api-toxin) has been widely used in the treatment of some immune-
related diseases, as well as in recent times in treatment of tumors. Several cancer cells …

For many cancers, there is a real need for more effective therapies. Although many drugs
show promising results in vitro, most fail to translate into an in vivo model system, and only∼ …

What do we know about Ki-67, apart from its usefulness as a cell proliferation biomarker in
histopathology? Discovered in 1983, the protein and its regulation of expression and …

In vitro 3D cancer models that provide a more accurate representation of disease in vivo are
urgently needed to improve our understanding of cancer pathology and to develop better …