An update on antiphospholipid syndrome

E Xourgia, MG Tektonidou - Current Rheumatology Reports, 2021 - Springer
Abstract Purpose of Review To review the recent available evidence on epidemiology,
pathogenesis, clinical phenotypes, and management of antiphospholipid syndrome (APS) …

Rethinking antiphospholipid syndrome to guide future management and research

JS Knight, D Erkan - Nature Reviews Rheumatology, 2024 - nature.com
Antiphospholipid syndrome (APS) consists of thrombotic, non-thrombotic and obstetric
clinical manifestations develo** in individuals with persistent antiphospholipid antibodies …

[HTML][HTML] Системная красная волчанка и антифосфолипидный синдром: вчера, сегодня, завтра

ЕЛ Насонов, ТМ Решетняк, СК Соловьев… - Терапевтический …, 2023 - cyberleninka.ru
Иммуновоспалительные (аутоиммунные и аутовоспалительные) ревматические
заболевания-не только весьма распространенные и тяжелые хронические …

Open-label, prospective, phase II descriptive pilot trial of belimumab therapy for refractory and/or non-criteria manifestations of antiphospholipid syndrome: study …

S Sciascia, M Radin, I Cecchi, A Barinotti… - Clinical and …, 2023 - iris.unito.it
To evaluate the safety and tolerability of belimumab given for 24 months in patients
persistently positive for antiphospholipid antibodies (aPL) with clinical features attributable …

Association of anti-β2-glycoprotein I/HLA-DR complex antibody with arterial thrombosis in female patients with systemic rheumatic diseases

K Yoneda, Y Ueda, K Tanimura, H Arase… - Arthritis Research & …, 2023 - Springer
Background β2-glycoprotein I (β2GPI) complexed with human leukocyte antigen DR
(β2GPI/HLA-DR) was found to be a major autoantibody target in antiphospholipid syndrome …

Disentangling the riddle of systemic lupus erythematosus with antiphospholipid syndrome: blood transcriptome analysis reveals a less-pronounced IFN-signature and …

D Nikolopoulos, C Loukogiannaki, G Sentis… - Annals of the …, 2024 - ard.bmj.com
Introduction Systemic lupus erythematosus with antiphospholipid syndrome (SLE-APS)
represents a challenging SLE endotype whose molecular basis remains unknown. Methods …

Type I interferon pathway activation across the antiphospholipid syndrome spectrum: associations with disease subsets and systemic antiphospholipid syndrome …

I Cecchi, M Radin, A Barinotti, SG Foddai… - Frontiers in …, 2024 - frontiersin.org
Introduction While the type I interferon (IFN-I) pathway is crucial in autoimmunity, its role in
antiphospholipid antibody (aPL)-positive subjects, including aPL carriers and …

[HTML][HTML] Antiphospholipid Antibodies as Key Players in Systemic Lupus Erythematosus: The Relationship with Cytokines and Immune Dysregulation

P Richter, MC Badescu, C Rezus, A Ouatu… - International Journal of …, 2024 - mdpi.com
Systemic lupus erythematosus (SLE) is a chronic autoimmune disease characterized by an
overproduction of cytokines, such as interleukins and interferons, contributing to systemic …

High-throughput sequencing technology facilitates the discovery of novel biomarkers for antiphospholipid syndrome

Q Liu, S Yang, Y Tan, L Cui - Frontiers in immunology, 2023 - frontiersin.org
Antiphospholipid syndrome (APS) is characterized by arterial and venous thrombosis and/or
morbid pregnancy, accompanied by persistent antiphospholipid antibody (aPL) positivity …

Systemic lupus erythematosus and antiphospholipid syndrome: past, present, future

EL Nasonov, TM Reshetnyak, SK Solovyev… - Terapevticheskii …, 2023 - ter-arkhiv.ru
Immune-inflammatory (autoimmune and autoinflammatory) rheumatic diseases are
widespread severe chronic inflammatory diseases and also “models” for studying the …