High-throughput glycomic methods
I Trbojević-Akmačić… - Chemical …, 2022 - ACS Publications
Glycomics aims to identify the structure and function of the glycome, the complete set of
oligosaccharides (glycans), produced in a given cell or organism, as well as to identify …
oligosaccharides (glycans), produced in a given cell or organism, as well as to identify …
[HTML][HTML] Immunoglobulin G glycosylation in aging and diseases
Abstract The Immunoglobulin G (IgG) glycome is well known for its heterogeneity and shows
a significant degree of variation within populations. IgG glycome composition is influenced …
a significant degree of variation within populations. IgG glycome composition is influenced …
Plasma markers of disrupted gut permeability in severe COVID-19 patients
A disruption of the crosstalk between the gut and the lung has been implicated as a driver of
severity during respiratory-related diseases. Lung injury causes systemic inflammation …
severity during respiratory-related diseases. Lung injury causes systemic inflammation …
[HTML][HTML] Hallmarks of glycosylation in cancer
Aberrant glycosylation plays a fundamental role in key pathological steps of tumour
development and progression. Glycans have roles in cancer cell signalling, tumour cell …
development and progression. Glycans have roles in cancer cell signalling, tumour cell …
[HTML][HTML] IgG glycans in health and disease: Prediction, intervention, prognosis, and therapy
Immunoglobulin (IgG) glycosylation is a complex enzymatically controlled process, essential
for the structure and function of IgG. IgG glycome is relatively stable in the state of …
for the structure and function of IgG. IgG glycome is relatively stable in the state of …
[HTML][HTML] Aberrant protein glycosylation: Implications on diagnosis and Immunotherapy
Glycosylation-mediated post-translational modification is critical for regulating many
fundamental processes like cell division, differentiation, immune response, and cell-to-cell …
fundamental processes like cell division, differentiation, immune response, and cell-to-cell …
Sialylation is involved in cell fate decision during development, reprogramming and cancer progression
F Li, J Ding - Protein & cell, 2019 - academic.oup.com
Sialylation, or the covalent addition of sialic acid to the terminal end of glycoproteins, is a
biologically important modification that is involved in embryonic development …
biologically important modification that is involved in embryonic development …
Aberrant glycosylation and cancer biomarker discovery: a promising and thorny journey
M Wang, J Zhu, DM Lubman, C Gao - Clinical Chemistry and …, 2019 - degruyter.com
Glycosylation is among the most important post-translational modifications for proteins and
is of intrinsic complex character compared with DNAs and naked proteins. Indeed, over 50 …
is of intrinsic complex character compared with DNAs and naked proteins. Indeed, over 50 …
[HTML][HTML] Environmental impacts, exposure pathways, and health effects of PFOA and PFOS
Per-and polyfluoroalkyl substances (PFAS) are synthetic chemicals that have been widely
utilized in various industries since the 1940s, and have now emerged as environmental …
utilized in various industries since the 1940s, and have now emerged as environmental …
Glycosylation of immunoglobulin G associates with clinical features of inflammatory bowel diseases
Background and Aims Causes of inflammatory bowel diseases are not well understood and
the most prominent forms, Crohn's disease (CD) and ulcerative colitis (UC), are sometimes …
the most prominent forms, Crohn's disease (CD) and ulcerative colitis (UC), are sometimes …