High-throughput glycomic methods

I Trbojević-Akmačić… - Chemical …, 2022 - ACS Publications
Glycomics aims to identify the structure and function of the glycome, the complete set of
oligosaccharides (glycans), produced in a given cell or organism, as well as to identify …

[HTML][HTML] Immunoglobulin G glycosylation in aging and diseases

I Gudelj, G Lauc, M Pezer - Cellular Immunology, 2018 - Elsevier
Abstract The Immunoglobulin G (IgG) glycome is well known for its heterogeneity and shows
a significant degree of variation within populations. IgG glycome composition is influenced …

Plasma markers of disrupted gut permeability in severe COVID-19 patients

LB Giron, H Dweep, X Yin, H Wang, M Damra… - Frontiers in …, 2021 - frontiersin.org
A disruption of the crosstalk between the gut and the lung has been implicated as a driver of
severity during respiratory-related diseases. Lung injury causes systemic inflammation …

[HTML][HTML] Hallmarks of glycosylation in cancer

J Munkley, DJ Elliott - Oncotarget, 2016 - ncbi.nlm.nih.gov
Aberrant glycosylation plays a fundamental role in key pathological steps of tumour
development and progression. Glycans have roles in cancer cell signalling, tumour cell …

[HTML][HTML] IgG glycans in health and disease: Prediction, intervention, prognosis, and therapy

S Shkunnikova, A Mijakovac, L Sironic, M Hanic… - Biotechnology …, 2023 - Elsevier
Immunoglobulin (IgG) glycosylation is a complex enzymatically controlled process, essential
for the structure and function of IgG. IgG glycome is relatively stable in the state of …

[HTML][HTML] Aberrant protein glycosylation: Implications on diagnosis and Immunotherapy

R Bangarh, C Khatana, S Kaur, A Sharma… - Biotechnology …, 2023 - Elsevier
Glycosylation-mediated post-translational modification is critical for regulating many
fundamental processes like cell division, differentiation, immune response, and cell-to-cell …

Sialylation is involved in cell fate decision during development, reprogramming and cancer progression

F Li, J Ding - Protein & cell, 2019 - academic.oup.com
Sialylation, or the covalent addition of sialic acid to the terminal end of glycoproteins, is a
biologically important modification that is involved in embryonic development …

Aberrant glycosylation and cancer biomarker discovery: a promising and thorny journey

M Wang, J Zhu, DM Lubman, C Gao - Clinical Chemistry and …, 2019 - degruyter.com
Glycosylation is among the most important post-translational modifications for proteins and
is of intrinsic complex character compared with DNAs and naked proteins. Indeed, over 50 …

[HTML][HTML] Environmental impacts, exposure pathways, and health effects of PFOA and PFOS

SY Wee, AZ Aris - Ecotoxicology and Environmental Safety, 2023 - Elsevier
Per-and polyfluoroalkyl substances (PFAS) are synthetic chemicals that have been widely
utilized in various industries since the 1940s, and have now emerged as environmental …

Glycosylation of immunoglobulin G associates with clinical features of inflammatory bowel diseases

M Šimurina, N de Haan, F Vučković, NA Kennedy… - Gastroenterology, 2018 - Elsevier
Background and Aims Causes of inflammatory bowel diseases are not well understood and
the most prominent forms, Crohn's disease (CD) and ulcerative colitis (UC), are sometimes …