Atopic dermatitis (AD) is the most common inflammatory skin disease worldwide, affecting
20% of children and 5% of adults. One critical component in the pathophysiology of AD is …

Psoriasis and atopic dermatitis fall within the category of cutaneous immune-mediated
inflammatory diseases (IMIDs). The prevalence of IMIDs is increasing in industrialized …

Loss-of-function (LoF) variants in the filaggrin (FLG) gene are the strongest known genetic
risk factor for atopic dermatitis (AD), but the impact of these variants on AD outcomes is …

Studies of asthma and allergy are generating increasing volumes of omics data for analysis
and interpretation. The National Institute of Allergy and Infectious Diseases (NIAID) …

Importance The epidemiological link between immune-mediated diseases (IMIDs) and
cardiovascular disease has often been attributed to systemic inflammation. However, the …

Dysregulated signaling from TNF and TNFR proteins is implicated in several immune-
mediated inflammatory diseases (IMIDs). This review centers around seven IMIDs …

Atopic dermatitis (AD) is an abnormal inflammatory response in the skin to food,
environmental IgE, or non-IgE allergens. This disease belongs to a group of inflammatory …

Background Observational studies have indicated that the plasma lipid profiles of patients
with atopic dermatitis show significant differences compared to healthy individuals …

The increased risk of food allergy in infants with atopic dermatitis has long been recognized;
an epidemiologic phenomenon termed “the atopic march.” Current literature supports the …

The purpose of this study was to identify the heterogeneity of atopic dermatitis and to identify
key genetic factors. This can lead to new approaches and personalized treatment strategies …