The use of eco-compatible synthetic procedures in organic reactions and, in particular, in 1,
3-dipolar cycloaddition reactions, has recently received a great deal of attention and …

Background: Bisphosphonates are drugs commonly used for the medication and prevention
of diseases caused by decreased mineral density. Despite such important medicinal use …

Polyurethanes (PUs) are very versatile and popular polymers that play a key role in the
automotive, construction and non-food consumable sectors. In general, two-step …

Post-translational lipid modifications farnesylation and geranylgeranylation of proteins
(protein prenylation) have been identified to mediate critical events in cancer, cardiovascular …

The syntheses of hydroxymethylenebisphosphonic acid derivatives (dronic acid derivatives)
starting from the corresponding substituted acetic acids and P-reagents, mainly phosphorus …

The use of microwave irradiation in organic chemistry and, in particular in 1, 3-dipolar
cycloaddition has recently gained much attention and great progress has been …

Objective Orthodontically induced inflammatory root resorption (OIIRR) is considered to be
an important sequel associated with orthodontic tooth movement (OTM). OTM after Socket …

Background: Methylenebisphosphonic derivatives including hydroxy-
methylenebisphosphonic species may be of potential biological activity, and a part of them is …

The synthesis of a small collection of novel bile acid–bisphosphonate (BA–BP) conjugates
as potential drug candidates is reported. The disclosed methodology relied on the …

We report herein the synthesis and biological evaluation of novel deoxynucleoside–bile acid
conjugates linked through a 1, 2, 3-triazole ring. The conjugates were synthesized via Cu (I) …