Classical electrostatics in biology and chemistry

B Honig, A Nicholls - Science, 1995 - science.org
A major revival in the use of classical electrostatics as an approach to the study of charged
and polar molecules in aqueous solution has been made possible through the development …

[PDF][PDF] Implicit solvation models: equilibria, structure, spectra, and dynamics

CJ Cramer, DG Truhlar - Chemical Reviews, 1999 - Citeseer
The present review is concerned with continuum and other implicit models of solvation
effects. We will concentrate on the elements required to make such models successful and …

Molecular dynamics: survey of methods for simulating the activity of proteins

SA Adcock, JA McCammon - Chemical reviews, 2006 - ACS Publications
The term molecular mechanics (MM) refers to the use of simple potential-energy functions
(eg, harmonic oscillator or Coulombic potentials) to model molecular systems. Molecular …

Generalized born models of macromolecular solvation effects

D Bashford, DA Case - Annual review of physical chemistry, 2000 - annualreviews.org
▪ Abstract It would often be useful in computer simulations to use a simple description of
solvation effects, instead of explicitly representing the individual solvent molecules …

Dielectric continuum methods for quantum chemistry

JM Herbert - Wiley Interdisciplinary Reviews: Computational …, 2021 - Wiley Online Library
This review describes the theory and implementation of implicit solvation models based on
continuum electrostatics. Within quantum chemistry this formalism is sometimes …

Improved generalized born solvent model parameters for protein simulations

H Nguyen, DR Roe, C Simmerling - Journal of chemical theory …, 2013 - ACS Publications
The generalized Born (GB) model is one of the fastest implicit solvent models, and it has
become widely adopted for Molecular Dynamics (MD) simulations. This speed comes with …

The Poisson–Boltzmann equation for biomolecular electrostatics: a tool for structural biology

F Fogolari, A Brigo, H Molinari - Journal of Molecular …, 2002 - Wiley Online Library
Electrostatics plays a fundamental role in virtually all processes involving biomolecules in
solution. The Poisson–Boltzmann equation constitutes one of the most fundamental …

Generalized born model with a simple smoothing function

W Im, MS Lee, CL Brooks III - Journal of computational …, 2003 - Wiley Online Library
Based on recent developments in generalized Born (GB) theory that employ rapid volume
integration schemes (MS Lee, FR Salabury, Jr., and CL Brooks III, J Chem Phys 2002, 116 …

Performance comparison of generalized born and Poisson methods in the calculation of electrostatic solvation energies for protein structures

M Feig, A Onufriev, MS Lee, W Im… - Journal of …, 2004 - Wiley Online Library
This study compares generalized Born (GB) and Poisson (PB) methods for calculating
electrostatic solvation energies of proteins. A large set of GB and PB implementations from …

Coupling of mechanical deformation and electromagnetic fields in biological cells

M Torbati, K Mozaffari, L Liu, P Sharma - Reviews of Modern Physics, 2022 - APS
The cell, as the most fundamental unit of life, is a microcosm of biology in which the
confluence of nearly all aspects of classical physics (mechanics, statistical physics …