Background Recent cohort studies show that salt intake below 6 g is associated with
increased mortality. These findings have not changed public recommendations to lower salt …

Background A reduction in salt intake lowers blood pressure (BP) and, thereby, reduces
cardiovascular risk. A recent meta‐analysis by Graudal implied that salt reduction had …

Background The question of whether reduced sodium intake is effective as a health
prophylaxis initiative is unsolved. The purpose was to estimate the effects of low-sodium vs …

Salt (sodium chloride) is an essential nutrient required to maintain physiological functions.
However, for most people, daily salt intake far exceeds their physiological need and is …

The assessment of salt sensitivity of blood pressure is difficult because of the lack of
universal consensus on definition. Regardless of the variability in the definition of salt …

All of the components of a complete dopamine system are present within the kidney, where
dopamine acts as a paracrine substance in the control of sodium excretion. Dopamine …

Dopamine is an important regulator of systemic blood pressure via multiple mechanisms. It
affects fluid and electrolyte balance by its actions on renal hemodynamics and epithelial ion …

Dopamine plays an important role in the pathogenesis of hypertension by regulating
epithelial sodium transport, vascular smooth muscle contractility and production of reactive …

Complex interactions between genes and environment result in a sodium-induced elevation
in blood pressure (salt sensitivity) and/or hypertension that lead to significant morbidity and …

Abnormalities in dopamine production and receptor function have been described in human
essential hypertension and rodent models of genetic hypertension. Under normal …