Actinomycetes: still a source of novel antibiotics

O Genilloud - Natural product reports, 2017 - pubs.rsc.org
Covering: 2006 to 2017 Actinomycetes have been, for decades, one of the most important
sources for the discovery of new antibiotics with an important number of drugs and analogs …

[HTML][HTML] Actinobacteria in natural products research: Progress and prospects

PA Jose, A Maharshi, B Jha - Microbiological research, 2021 - Elsevier
Actinobacteria are well-recognised biosynthetic factories that produce an extensive
spectrum of secondary metabolites. Recent genomic insights seem to impact the exploitation …

antiSMASH 3.0—a comprehensive resource for the genome mining of biosynthetic gene clusters

T Weber, K Blin, S Duddela, D Krug… - Nucleic acids …, 2015 - academic.oup.com
Microbial secondary metabolism constitutes a rich source of antibiotics, chemotherapeutics,
insecticides and other high-value chemicals. Genome mining of gene clusters that encode …

Microalgae cultivation strategies using cost–effective nutrient sources: Recent updates and progress towards biofuel production

RG Saratale, VK Ponnusamy, RB Jeyakumar… - Bioresource …, 2022 - Elsevier
Scientists are grabbing huge attention as well as consciousness on non–renewable energy
sources for the global energy crises because of gradual increase in oil price, fast depletion …

The evolution of genome mining in microbes–a review

N Ziemert, M Alanjary, T Weber - Natural product reports, 2016 - pubs.rsc.org
Covering: 2006 to 2016 The computational mining of genomes has become an important
part in the discovery of novel natural products as drug leads. Thousands of bacterial …

Discovery of microbial natural products by activation of silent biosynthetic gene clusters

PJ Rutledge, GL Challis - Nature reviews microbiology, 2015 - nature.com
Microorganisms produce a wealth of structurally diverse specialized metabolites with a
remarkable range of biological activities and a wide variety of applications in medicine and …

Physiological limitations and opportunities in microbial metabolic engineering

J Montaño López, L Duran, JL Avalos - Nature Reviews Microbiology, 2022 - nature.com
Metabolic engineering can have a pivotal role in increasing the environmental sustainability
of the transportation and chemical manufacturing sectors. The field has already developed …

Production technologies, current role, and future prospects of biofuels feedstocks: A state-of-the-art review

A Callegari, S Bolognesi, D Cecconet… - Critical Reviews in …, 2020 - Taylor & Francis
Fossil fuel continued overuse and carbon emissions issues have prompted increased
research efforts on sustainable and renewable energy sources as alternative to fossil fuels …

CRISPR-Cas9 based engineering of actinomycetal genomes

Y Tong, P Charusanti, L Zhang, T Weber… - ACS synthetic …, 2015 - ACS Publications
Bacteria of the order Actinomycetales are one of the most important sources of
pharmacologically active and industrially relevant secondary metabolites. Unfortunately …

Diversity and applications of endophytic actinobacteria of plants in special and other ecological niches

R Singh, AK Dubey - Frontiers in microbiology, 2018 - frontiersin.org
Actinobacteria are wide spread in nature and represent the largest taxonomic group within
the domain Bacteria. They are abundant in soil and have been extensively explored for their …