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Predictive overfitting in immunological applications: Pitfalls and solutions
Overfitting describes the phenomenon where a highly predictive model on the training data
generalizes poorly to future observations. It is a common concern when applying machine …
generalizes poorly to future observations. It is a common concern when applying machine …
Semi-supervised Omics Factor Analysis (SOFA) disentangles known and latent sources of variation in multi-omic data
Abstract Group Factor Analysis is a family of methods for representing patterns of correlation
between features in tabular data. Argelaguet et al. identify latent factors within and across …
between features in tabular data. Argelaguet et al. identify latent factors within and across …
Dimensionality reduction methods for high-dimensional biological data analysis
KT Capraz - 2024 - archiv.ub.uni-heidelberg.de
Disease progression and response to treatments can strongly differ between patients, due to
each individual's unique genetic, environmental and molecular factors. Precision medicine …
each individual's unique genetic, environmental and molecular factors. Precision medicine …
Supervised Integration of Multi-Omics Immune Profiles via Latent Factor Modeling
J Gygi - 2024 - search.proquest.com
Advances in high-throughput technologies such as RNA-seq, metabolomics, proteomics,
and cytometry have enabled the simultaneous collection of vast amounts of high …
and cytometry have enabled the simultaneous collection of vast amounts of high …