The brain requires over one-fifth of the total body oxygen demand for normal functioning. At
high altitude (HA), the lower atmospheric oxygen pressure inevitably challenges the brain …

Erythropoietin (EPO) is a cytokine mainly induced in hypoxia conditions. Its major production
site is the kidney. EPO primarily acts on the erythroid progenitor cells in the bone marrow …

In recent years, exploring natural compounds with functional properties to ameliorate aging-
associated cognitive decline has become a research priority to ensure healthy aging. In the …

Erythropoietin (Epo), the main erythropoiesis‐stimulating factor widely prescribed to
overcome anemia, is also known nowadays for its cytoprotective action on non …

Persistent neuroinflammation is now recognized as a chief pathological component of
practically all neurodegenerative diseases. Neuroinflammation in the central nervous …

Acute as well as chronic disorders of the nervous system lead to significant morbidity and
mortality for millions of individuals globally. Given the ability to govern stem cell proliferation …

Metabolic disorders, such as diabetes mellitus (DM), are increasingly becoming significant
risk factors for the health of the global population and consume substantial portions of the …

The purpose of this study was to explore how liraglutide affects AD-like pathology and
cognitive function in APP/PS1/Tau triple transgenic (3× Tg) Alzheimer disease (AD) model …

Multiple genetic, metabolic, and environmental abnormalities are known to contribute to the
pathogenesis of Alzheimer's dementia (AD). If all of those abnormalities were addressed it …

Recent studies have indicated that environmental enrichment (EE) increases the sensorial
and social stimulations and leads to strengthened plastic changes in the brain. In models of …