Central nervous system regeneration: the roles of glial cells in the potential molecular mechanism underlying remyelination

L Quan, A Uyeda, R Muramatsu - Inflammation and regeneration, 2022 - Springer
Glial cells play crucial roles in brain homeostasis and pathogenesis of central nervous
system (CNS) injuries and diseases. However, the roles of these cells and the molecular …

Efficacy and safety of masitinib in progressive forms of multiple sclerosis: a randomized, phase 3, clinical trial

P Vermersch, L Brieva-Ruiz, RJ Fox, F Paul… - Neurology …, 2022 - neurology.org
Background and Objectives Masitinib is a selective tyrosine kinase inhibitor, targeting innate
immune cells (mast cells and microglia) that are involved in the pathophysiology of …

A narrative review on axonal neuroprotection in multiple sclerosis

N Collongues, G Becker, V Jolivel… - Neurology and …, 2022 - Springer
Multiple sclerosis (MS) is a chronic inflammatory disease of the central nervous system
(CNS) resulting in demyelination and neurodegeneration. The therapeutic strategy is now …

A deep learning approach to predicting disease progression in multiple sclerosis using magnetic resonance imaging

L Storelli, M Azzimonti, M Gueye, C Vizzino… - Investigative …, 2022 - journals.lww.com
Objectives Magnetic resonance imaging (MRI) is an important tool for diagnosis and
monitoring of disease course in multiple sclerosis (MS). However, its prognostic value for …

The current standing of autologous haematopoietic stem cell transplantation for the treatment of multiple sclerosis

AG Willison, T Ruck, G Lenz, HP Hartung… - Journal of neurology, 2022 - Springer
Autologous haematopoietic stem cell transplantation (aHSCT) is gaining traction as a
valuable treatment option for patients affected by severe multiple sclerosis (MS), particularly …

Occurrence and severity of coronavirus disease 2019 are associated with clinical disability worsening in patients with multiple sclerosis

G Peeters, A Van Remoortel, G Nagels… - Neurology …, 2023 - neurology.org
Background and Objectives Large-scale observational studies have shown that, in patients
with multiple sclerosis (MS), the risk of becoming more severely ill from coronavirus disease …

Protocol of a prospective multicenter study on comorbidity impact on multiple sclerosis and antibody-mediated diseases of the central nervous system (COMMIT)

S Samadzadeh, R Adnan, P Berglova… - Frontiers in …, 2024 - frontiersin.org
Comorbidities in patients with multiple sclerosis (MS) and antibody-mediated diseases of the
central nervous system (CNS) including neuromyelitis optica spectrum disorder (NMOSD) …

A Self‐Reported Study on Explanatory Variables of Stress in Multiple Sclerosis Patients: Exploring the Effect of Physical Conditions and Emotion Regulation …

T Carvalho, A Sousa‐Mendes… - Clinical psychology …, 2024 - Wiley Online Library
Background Multiple sclerosis (MS)‐linked stress is frequent, multidetermined and facilitates
the onset/exacerbation of MS. However, few explanatory models of stress analysed the joint …

[HTML][HTML] Primary Progressive Multiple Sclerosis—A Key to Understanding and Managing Disease Progression

I Sempik, E Dziadkowiak, H Moreira, A Zimny… - International Journal of …, 2024 - mdpi.com
Primary progressive multiple sclerosis (PPMS), the least frequent type of multiple sclerosis
(MS), is characterized by a specific course and clinical symptoms, and it is associated with a …

[HTML][HTML] MSProDiscuss™ clinical decision support tool for identifying multiple sclerosis progression

T Ziemssen, J Vandercappellen… - Journal of Clinical …, 2022 - mdpi.com
This article describes the rationale for the development of the MSProDiscuss™ clinical
decision support (CDS) tool, its development, and insights into how it can help neurologists …