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IMI–Report on experimental models of emmetropization and myopia
D Troilo, EL Smith, DL Nickla, R Ashby… - … & visual science, 2019 - iovs.arvojournals.org
The results of many studies in a variety of species have significantly advanced our
understanding of the role of visual experience and the mechanisms of postnatal eye growth …
understanding of the role of visual experience and the mechanisms of postnatal eye growth …
Animal models in myopia research
F Schaeffel, M Feldkaemper - Clinical and Experimental Optometry, 2015 - Taylor & Francis
Our current understanding of the development of refractive errors, in particular myopia,
would be substantially limited had Wiesel and Raviola not discovered by accident that …
would be substantially limited had Wiesel and Raviola not discovered by accident that …
Augmentation of scleral glycolysis promotes myopia through histone lactylation
Myopia is characterized of maladaptive increases in scleral fibroblast-to-myofibroblast
transdifferentiation (FMT). Scleral hypoxia is a significant factor contributing to myopia, but …
transdifferentiation (FMT). Scleral hypoxia is a significant factor contributing to myopia, but …
Changes in choroidal thickness and choroidal blood perfusion in guinea pig myopia
S Zhang, G Zhang, X Zhou, R Xu… - … & visual science, 2019 - iovs.arvojournals.org
Purpose: The purpose of this study was to study changes in choroidal thickness (ChT) and
choroidal blood perfusion (ChBP), and the correlation between them, in guinea pig myopia …
choroidal blood perfusion (ChBP), and the correlation between them, in guinea pig myopia …
Increased choroidal blood perfusion can inhibit form deprivation myopia in guinea pigs
X Zhou, S Zhang, G Zhang, Y Chen… - … & Visual Science, 2020 - iovs.arvojournals.org
Purpose: In guinea pigs, choroidal thickness (ChT) and choroidal blood perfusion (ChBP)
simultaneously decrease in experimental myopia, and both increase during recovery …
simultaneously decrease in experimental myopia, and both increase during recovery …
Decreased choroidal blood perfusion induces myopia in guinea pigs
X Zhou, S Zhang, F Yang, Y Yang… - … & Visual Science, 2021 - iovs.arvojournals.org
Purpose: The development of myopia in guinea pigs can be inhibited by attenuating scleral
hypoxia by increasing choroidal blood perfusion (ChBP). In this study, we reduced ChBP …
hypoxia by increasing choroidal blood perfusion (ChBP). In this study, we reduced ChBP …
The relationship between anisometropia and amblyopia
This review aims to disentangle cause and effect in the relationship between anisometropia
and amblyopia. Specifically, we examine the literature for evidence to support different …
and amblyopia. Specifically, we examine the literature for evidence to support different …
[HTML][HTML] Interactions of chromatic and lens-induced defocus during visual control of eye growth in guinea pigs (Cavia porcellus)
It was recently demonstrated that chromaticity could affect eye growth and refractive
development in guinea pigs but it remained unclear whether correction with spectacle …
development in guinea pigs but it remained unclear whether correction with spectacle …
SWATH based quantitative proteomics reveals significant lipid metabolism in early myopic guinea pig retina
Most of the previous myopic animal studies employed a single-candidate approach and
lower resolution proteomics approaches that were difficult to detect minor changes, and …
lower resolution proteomics approaches that were difficult to detect minor changes, and …
Effects of dopaminergic agents on progression of naturally occurring myopia in albino guinea pigs (Cavia porcellus)
Purpose.: Disruption of dopaminergic signaling has been implicated in the abnormalities of
ocular development in albinism, and many experiments have shown that retinal dopamine is …
ocular development in albinism, and many experiments have shown that retinal dopamine is …