IMI–Report on experimental models of emmetropization and myopia

D Troilo, EL Smith, DL Nickla, R Ashby… - … & visual science, 2019 - iovs.arvojournals.org
The results of many studies in a variety of species have significantly advanced our
understanding of the role of visual experience and the mechanisms of postnatal eye growth …

Animal models in myopia research

F Schaeffel, M Feldkaemper - Clinical and Experimental Optometry, 2015 - Taylor & Francis
Our current understanding of the development of refractive errors, in particular myopia,
would be substantially limited had Wiesel and Raviola not discovered by accident that …

Augmentation of scleral glycolysis promotes myopia through histone lactylation

X Lin, Y Lei, M Pan, C Hu, B **e, W Wu, J Su, Y Li… - Cell Metabolism, 2024 - cell.com
Myopia is characterized of maladaptive increases in scleral fibroblast-to-myofibroblast
transdifferentiation (FMT). Scleral hypoxia is a significant factor contributing to myopia, but …

Changes in choroidal thickness and choroidal blood perfusion in guinea pig myopia

S Zhang, G Zhang, X Zhou, R Xu… - … & visual science, 2019 - iovs.arvojournals.org
Purpose: The purpose of this study was to study changes in choroidal thickness (ChT) and
choroidal blood perfusion (ChBP), and the correlation between them, in guinea pig myopia …

Increased choroidal blood perfusion can inhibit form deprivation myopia in guinea pigs

X Zhou, S Zhang, G Zhang, Y Chen… - … & Visual Science, 2020 - iovs.arvojournals.org
Purpose: In guinea pigs, choroidal thickness (ChT) and choroidal blood perfusion (ChBP)
simultaneously decrease in experimental myopia, and both increase during recovery …

Decreased choroidal blood perfusion induces myopia in guinea pigs

X Zhou, S Zhang, F Yang, Y Yang… - … & Visual Science, 2021 - iovs.arvojournals.org
Purpose: The development of myopia in guinea pigs can be inhibited by attenuating scleral
hypoxia by increasing choroidal blood perfusion (ChBP). In this study, we reduced ChBP …

The relationship between anisometropia and amblyopia

BT Barrett, A Bradley, TR Candy - Progress in retinal and eye research, 2013 - Elsevier
This review aims to disentangle cause and effect in the relationship between anisometropia
and amblyopia. Specifically, we examine the literature for evidence to support different …

[HTML][HTML] Interactions of chromatic and lens-induced defocus during visual control of eye growth in guinea pigs (Cavia porcellus)

L Jiang, S Zhang, F Schaeffel, S **ong, Y Zheng… - Vision research, 2014 - Elsevier
It was recently demonstrated that chromaticity could affect eye growth and refractive
development in guinea pigs but it remained unclear whether correction with spectacle …

SWATH based quantitative proteomics reveals significant lipid metabolism in early myopic guinea pig retina

J Bian, YH Sze, DYY Tse, CH To… - International journal of …, 2021 - mdpi.com
Most of the previous myopic animal studies employed a single-candidate approach and
lower resolution proteomics approaches that were difficult to detect minor changes, and …

Effects of dopaminergic agents on progression of naturally occurring myopia in albino guinea pigs (Cavia porcellus)

L Jiang, K Long, F Schaeffel, X Zhou… - … & visual science, 2014 - iovs.arvojournals.org
Purpose.: Disruption of dopaminergic signaling has been implicated in the abnormalities of
ocular development in albinism, and many experiments have shown that retinal dopamine is …